Flashcards in Limbic system - Hippocampus - amyg Deck (11):
- lesions where causes impairment in dec. mem?
ability to recollect events or facts that have a specfic temporal and spatial context.
ability to learn new motor skills
what kind of memory is affectd by lesions in frontal cortex?
short term memory
- lasts sec-min
_____ is the site for long term memory storage.
Hippocampus is important in formation and consolidation of _______ memory
long term declarative
- which is stored in neocortex
pt HM has had medial temporal lobe resection. He has problems in ______ memory, but not _____ memory
procedural memory (a-ok)
(aka had his hippocampus removed)
____ is imp in form of declarative memory.
_____ is imp in formation of procedural memory
- proc. mem: ability to learn new motor skills
How do hippocampal synapses undergo LTP?
Entorhinal cortex → (perforant path) → dentate gyrus → (mossy fibers) → CA3→ (Shaeffer cells) → CA1 → (feedbacks/autoassociation on C3) → entorhinal cortex
(Both CA1 and CA3 can undergo LTP)
- repeated stim. of CA3 or CA1 neurons lead to LTP
(both loc on Hippocampus)
Failure to maintain LTP in the hippocampus can be due to AB protein deposition
Kluver Bucy syndrome
removal of amygdala -
important in expression of emotion.
Conditioned flavor aversion (CFA)
eat food → widespread ACh spread throughout brain → insular cortex (taste response) → (NMDA P) → Amygdala
(if antagonists are perfused to insular cortex = no food aversion)
Projections from the Cerebellum are _____, but it affects ________
presents as ips