liver/biliary/panc Flashcards
(175 cards)
- Chan, VRU 2024. Canine primary liver tumors treated with stereotactic body radiation therapy: A case series
-clinical improvement %
-tumor dec %
-MST?
o clinical improvement in 33% dogs treated with SBRT
~50% dec in tumor volume
o MST= 164 d /5mo
- Mcalexander, JAVMA 2024. Diagnostic and surgical treatment for traumatic bile peritonitis in dogs and cats
survival rate?
site of rupture in cats vs dogs?
o 88.2% survival
o most frequent site of rupture: CBD = dogs ; cystic duct = cats
- Bentley, VRU 2024. Intra‐ and interobserver agreement in computed tomography localization of primary nonhematopoietic hepatic masses and comparison with surgical and histopathological outcomes in 21 cats
most common tumor in cats? what division?
o left hepatic division (54%)»
o most common = biliary cystadenoma (52%) and hepatocellular adenoma (29%) – benign tumors!
- Moore et al, Vet surg 2023. Association between divisional location and short-term outcome of liver mass resection in 124 dogs
-what 3 things were associated with dec complications?
-intraop comps inc __x if not using TA?
-odds of complication w R divisional mass?
o decreased likelihood of postop comps if: used a TA stapler, specialist surgeon, or larger/heavier dogs
odds of intraop complications were 19x higher if sx performed without a TA stapler
o RIGHT divisional mass = 88% higher chance of intraoperative complications
- Bergen, vet surg 2023. Clinical use of uncovered balloon‐expandable metallic biliary stents for treatment of extrahepatic biliary tract obstructions in cats and dogs: 11 cases (2012–2022)
complications?
obstruction w/ choledocholiths, recurr cholangiohepatitis
- Dobberstein, vet surg 2023. Comparison of the diagnostic yield of 3 and 5 mm laparoscopic liver biopsy forceps in cats
which size and “technique” recc?
5mm cup forceps; twist or pull tech
- Smola et al, JAVMA 2023. Computed tomography angiography aids in predicting resectability of isolated liver tumors in dogs.
3 factors affecting resectability?
3 factors affecting resectablity:
Major vascular involvement
multilobar involvement
right-sided laterality negatively affected resectability
- Jablonski, JVIM 2023. Concurrent hepatopathy in dogs with gallbladder mucocele: Prevalence, predictors, and impact on long‐term outcome
% of dogs w hepatic abN?
o 98% dogs with GBM had at least 1 hepatic histologic abnormality (fibrosis most common)
- Cleary, JAVMA 2023. Features, management, and long-term outcome in dogs with pancreatitis and bile duct obstruction treated medically and surgically: 41 dogs (2015–2021)
survival rate for sx vs medical ?
o Survival rate: surgery = 95% surgery vs 57% medical mgmt
- Burke, JVECC 2023. Hepatic abscessation in dogs: A multicenter study of 56 cases (2010–2019)
most common bacteria?
% w cancer?
survival rate?
how is this different than dickerson 2023 paper?
o E coli = most common
o 21% had neoplasia
o 71% survived to discharge –hypoglycemia & multifocal abscessation were assoc w dec survival
dickerson 2023 = 30% neoplasia, E colli most common, 63% survival
SIMILAR
- Ullal, JAVMA 2023. Increasing age and severe intraoperative hypotension associated with nonsurvival in dogs with gallbladder mucocele undergoing cholecystectomy
% survival to discharge?
2 factors associated with w/ nonsurvival?
76% survived
inc age & BP <65mmgh assoc w/ nonsurvival
- Larose, vet surg 2023. Near‐infrared fluorescence cholangiography in dogs: A pilot study
indication?
ID of biliary tears / bile leakage
- Brunori, JVIM 2023. Occurrence and clinical relevance of postoperative hypernatremia in dogs undergoing cholecystectomy
relationship bw hypernatremia and odds of death?
Na above what conc didn’t survive?
conclusion?
dvlpt of hypernatremia within 6 hours postop = 7.7 higher odds of nonsurvival
Change in Na >10 mEq = 3.3x higher odds of mortality
postop Na>160 mEq/L did not survive
hypernatremia common and may be associated with death – RELEVANT finding
- Dickerson et al, vet surg 2023. Outcome in 38 dogs surgically treated for hepatic abscessation.
most common bacteria?
% w cancer?
survival rate?
what comorbitidis were associated with inc risk for abscess dvlpt?
e coli; 30% cancer; 63% survived
(burke had similar)
o diabetes mellitus, hepatobiliary disease & panc = inc risk of developing hepatic abscessation
- Brunet, JVIM 2023. Prevalence and clinical relevance of cholelithiasis in cats: A multicenter retrospective study of 98 cases
% symptomatic vs incidental
o Incidental = 41% ; symptomatic = 59%
~60% symptomatic – mutliplle choleliths or EHBDO signs
- Hernon, vet surg 2023. The effect of flushing of the common bile duct on hepatobiliary markers and short‐term outcomes in dogs undergoing cholecystectomy for the management of gall bladder mucocele: A randomized controlled prospective study
mortality rate? findings?
o no difference in Tbili or LES bw flush vs no flush
o mortality rate = 9.7%
o findings of the study do not support routine flushing of the CBD during cholecystectomy
- Simpson, vet surg 2022. Cholecystectomy in 23 cats (2005‐2021)
mortality?
mortality rate = 21.7%
- Reist et al, JAVMA 2022. Histopathologic findings and survival outcomes of dogs undergoing liver lobectomy as treatment for spontaneous hemoabdomen secondary to a ruptured liver mass :retrospective analysis of 200 cases (2012–2020)
most common dx?
prognostic factors?
MST for HCC vs HSA?
o HCC (36%)» benign masses (27.5%)> hemangiosarcoma (25.5%)
o px factors for survival: histo dx, increased ALT, anemia, and whether a transfusion was received
o 64% of dogs with spont hemoab d/t liver mass had well-differentiated HCC or a benign process
MST: HCC 897d (2.5y) vs HSA 45d
- Piegols, vet surg 2021. Association between biliary tree manipulation and outcome in dogs undergoing cholecystectomy for gallbladder mucocele: A multi‐institutional retrospective study
what complications was associated with catheterization?
catheterized dogs were more likely to (3 things)
o Catheterized dogs = higher ASA scores, higher Tbili, and dilated CBD at time of sx
o pancreatitis assoc w/ CBD catheterization – not different bw normograde / retrograde catheterization
o Hernon 2023 recc no biliary flushing
- Griffin, JVIM 2021. Choledochal stenting for treatment of extrahepatic bile duct obstruction in cats
survival rate? recur rate? what was associated with recurrence
o Survival = 78%
o Recurrence = 38% – Cholelithiasis assoc w/ recurrence
- Center, JAVMA 2021. Clinical features, concurrent disorders, and survival time in cats with suppurative cholangitis-cholangiohepatitis syndrome.
postive bilary cultures?
sx vs med mgmt recc?
o + bacterial cultures = 69%
o Cholelithiasis (+/- EHBDO) and cholecystectomy were associated with survival advantages – cholecystoenterostomy had no survival impact sx = significant survival advantage
- Friesen, JSAP 2021. Clinical findings for dogs undergoing elective and nonelective cholecystectomies for gall bladder mucoceles
mortality rate
o 6% for elective cholecystectomy and 23% for nonelective
- Putterman, vet surg 2021. Influence of normograde versus retrograde catheterization of bile ducts in dogs treated for gallbladder mucocele
recc?
o retrograde = more complications than normograde
o Tbili decreased: 70% normograde vs 40% retro
o recommend NG > retrograde catheterization
(hernon 2023 = no benefit to flushing)
- Linden et al. Vet surg 2019. Outcomes and prognostic variables associated with central division hepatic lobectomies: 61 dogs
mortality? hemorrhage?
o hemorrhage = 33%
o mortality rate = 11%