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Child Medicine > Liver Disorders > Flashcards

Liver Disorders Flashcards

1
Q

What is Biliary Atresia?

A

The obliteration of the intra and extra hepatic biliary tree

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2
Q

Presentation of Biliary Atresia?

A

Mild jaundice and pale stools

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3
Q

What do investigations for Biliary Atresia reveal?

A

Raised GGT and conjugated bilirubin

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4
Q

How is the Biliary Atresia diagnosis confirmed?

A

Cholangiogram

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5
Q

Treatment for Biliary Atresia?

A

Surgery, Liver transplant if surgery fails

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6
Q

Investigation of neonatal hepatitis syndrome?

A

Urine sample and galactose 1 phosphate test

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7
Q

Treatment for neonatal hepatitis syndrome?

A

Galactose free diet

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8
Q

Alagille Syndrome presentation?

A

Triangular face, wide spaced eyes, pruritis, faltering growth

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9
Q

Investigation of Alagille Syndrome?

A

Confirm faltering growth

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10
Q

Treatment of Alagille Syndrome?

A

Fat soluble vitamins

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11
Q

Progressive familial intrahepatic cholestasis presentation?

A

Rickets, jaundice, intense pruritis

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12
Q

Investigation for Progressive Familial Intrahepatic cholestasis?

A

Identify gene mutations

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13
Q

Treatment for Progressive Familial Intrahepatic cholestasis?

A

IBAT

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14
Q

What is progressive familial Intrahepatic cholestasis?

A

AR disorder that affects bile transport

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15
Q

Hepatitis A transmission?

A

Feco oral

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16
Q

How to diagnose Hepatitis A?

A

IgM antibody

17
Q

What do we do with their close contacts

A

Vaccinate

18
Q

How is Hepatitis B spread

A

Sexually, Horizontally, or through blood transfusions

19
Q

Clinical signs of Hepatitis B?

A

Asymptomatic

20
Q

Diagnosis of hepatitis B?

A

HBV antigens

21
Q

Hepatitis C transmission?

A

Vertical, worsened if HIV too

22
Q

Hepatitis C treatment?

A

Oral direct acting antivirals

23
Q

What does Hepatitis D do?

A

Exacerbates HBV infection, depends on it for replication too

24
Q

How is Hepatitis E transmitted?

A

Enterally

25
Q

Hepatitis E presentation?

A

Mild self limiting illness

Child Medicine (40 decks)

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