lymphoma

Question 1

what

Answer 1

cancers affecting lymphocytes inside lymphatic system

cancer cells proliferate inside lymph nodes

Question 2

Hodgkin’s lymphoma

Answer 2

caused by proliferation of lymphocytes

Question 3

Hodgkin’s lymphoma : ages affected

Answer 3

bimodal peak

20yrs and 75yrs

Question 4

Hodgkin’s lymphoma: risk factors

Answer 4

HIV
EBV
autoimmune e.g. RA, sarcoid
FHx

Question 5

Hodgkin’s lymphoma: presentation

Answer 5

lymphadenopathy 
B symptoms 
fatigue 
itching 
SOB 
abdo pain 
recurrent infections

Question 6

b symptoms

Answer 6

fever
weight loss
night sweats

Question 7

Hodgkin’s lymphoma: Ix

Answer 7

LDH

lymph node biopsy

Question 8

Hodgkin’s lymphoma: key finding from lymph node biopsy

Answer 8

reed-sternberg cells

Question 9

reed-sternberg cells

Answer 9

abnormally large B cells
multiple nuclei with nucleoli within them

(appearance of face of owl with large eyes)

Question 10

Ann Arbor staging: 1

Answer 10

confined to one region of nodes

Question 11

Ann Arbor staging: 2

Answer 11

in more than one region but same side of diaphragm

Question 12

Ann Arbor staging: 3

Answer 12

affects lymph nodes above and below diaphraghm

Question 13

Ann Arbor staging: 4

Answer 13

widespread involvement incl non lymphatic organs e.g. lung, liver

Question 14

Hodgkins Lymphome Mx

Answer 14

chemo

radiotherapy

Question 15

Non-Hodgkin Lymphoma: risk factors

Answer 15

HIV 
EBV
h.pylori
hep B or c
FHx