M&R 2 (Resting cell membrane + Electrical excitability) Flashcards Preview

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Flashcards in M&R 2 (Resting cell membrane + Electrical excitability) Deck (13):
1

What is the concentration of Na+ in the ICF and ECF?

ICF = 10 mM
ECF = 145 mM

2

What is the concentration of K+ in the ICF and ECF?

ICF = 160 mM
ECF = 4.5 mM

3

What is the concentration of Cl- in the ICF and ECF?

ICF = 3 mM
ECF = 120 mM

4

What is the concentration of anions in the ICF and ECF?

ICF = 167 mM
ECF = 40 mM

5

Define the resting membrane potential:

Difference in electrical potential between the inside and outside of a cell (expressed as potential inside relative to outside, as ECM = 0 mV).
Arises due to increased permeability to K+ at rest

6

What is the potential of the extracellular matrix?

0 mV

7

What is the equilibrium potential of K+?

-95 mV

8

What is the equilibrium potential of Na+?

+70 mV

9

What is the equilibrium potential of Ca2+?

+122 mV

10

What is the equilibrium potential of Cl-?

-85 mV

11

Will the opening of K+ or Cl- channels cause hyperpolarisation or depolarisation of the cell?

Hyperpolarisation

12

Will the opening of Na+ or Ca2+ channels cause hyperpolarisation or depolarisation of the cell?

Depolarisation

13

Define the equilibrium potential of an ion:

The membrane potential when the electrical and diffusional forces balance = no net movement of that ion.