MALARIAL PARASITES (Plasmodium spp.)

Question 1

Which Life Cycle of Malarial Parasite?

• Female Anopheles mosquito is the Defintiive host
• Sporogony

Answer 1

Sexual Phase

Question 2

Which Life Cycle of Malarial Parasite?

• Man or other vertebrates (e.g. monkey) is Intermediate Host
• Schizogony
• Gametogony

Answer 2

Asexual Phase

Question 3

Appearance of parasitized RBC: Normal; multiple infection of RBC very common

Age of RBC infected: ALL AGES

Answer 3

P. falciparum

Question 4

Appearance of parasitized RBC: Larger than normal, pale, and oval to normal in shape

Age of RBC infected: YOUNG AGES

Answer 4

P. vivax

Question 5

Appearance of parasitized RBC: Larger than normal, oval and may have fimbriated edges

Age of RBC infected: YOUNG AGES

Answer 5

P. ovale

Question 6

Appearance of parasitized RBC: Normal in shape; size may be normal or slightly smaller

Age of RBC infected: OLD AGES

Answer 6

P. malariae

Question 7

stain for RBC stippling

Answer 7

Giemsa stain

Question 8

RBC stippling of P. falciparum

Answer 8

Maurer`s dots (occasional)

Question 9

RBC stippling of P. vivax

Answer 9

Schuffner`s dots (common)

Question 10

RBC stippling of P. ovale

Answer 10

James` dots

Question 11

RBC stippling of P. malariae

Answer 11

Ziemann`s dots (rare)

Question 12

Length of erythrocytic cycle / PERIODICITY

1. Quotidian (every 24 hours)
2. Tertian ( every 48 hours)
3. Quartan (every 72 hours)

Answer 12

1. P. knowlesi
2. P. vivax, P. ovale, & P. falciparum (36 hours)
3. P. malariae

Question 13

most fatal type caused by

Answer 13

P. falciparum

Question 14

Malignant tertian malaria by P. falciparum is manifested by

Answer 14

Black water fever

Question 15

Relapse may occur with _______________________ infections due to reactivation of ________________
in the liver.

Answer 15

P. vivax and P. ovale

Hypnozoites

Question 16

Incubation period of Malaria

Answer 16

8-40 days

Question 17

Classical sign: _______________ characterized by ___, ___, and ___

Answer 17

PAROXYSM

chiils, fever, and profuse sweating

Question 18

Acquired resistance is associated with certain genetic conditions

Sickle trait:
Duffy negative blood group:

Answer 18

Sickle trait: P. falciparum

Duffy negative blood group: P. vivax

Question 19

Simian or 5th Human Malaria

Answer 19

Plasmodium knowlesi

Question 20

P. knowlesi – young forms resemble _____________________ while mature forms resemble

Answer 20

young forms: P. falciparum

mature forms: P. malariae

Question 21

MICROmetocyte (Male) Characteristic: (P. falciparum)

1. end is
2. chromatin granules

Answer 21

1. end is ROUNDED
2. chromatin granules is SCATTERED

Question 22

MACROmetocyte (Female) Characteristic: (P. falciparum)

1. end is
2. chromatin granules

Answer 22

1. end is POINTED or Crescent shape
2. chromatin granules is CENTRAL

Question 23

which plasmodium have a rosette or daisy formation of schizont

Answer 23

P. malariae