Male Histology & VM - Bolender Flashcards Preview

M2 Endo/Repro > Male Histology & VM - Bolender > Flashcards

Flashcards in Male Histology & VM - Bolender Deck (13):
1

What are the functions of Sertoli cells?

  • Structural metabolic support for developing spermatogenic cells
  • isolation of spermatogenic cells from the immune system
  • phagocytose cytoplasm
  • secrete tubular fluid
  • secrete inhibin
  • establish blood / testis barrier 

2

Interstitial cells of Leydig secrete...?

testosterone

3

What kind of epithelium lines the rete testis?

The epididymis?

The ducus deferens?

The penile urethra?

simple cuboidal

pseudostratified

pseudostratified

stratified columnar or pseudostratified

4

Sperm undergo what process in the epididymis?

maturation and competence for motility

5

Do spermatozoa pass through the seminal vesicles?

What is the function of the seminal vesicles?

No (but apparently they can end up there incidentally)

secretion of seminal fluid (60% of semen volume): fructose, prostaglandins, seminogelin 

6

Identify

Q image thumb

Ductus (Vas) deferens

7

Identify

Q image thumb

Prostatic concretion

8

Identify

Q image thumb

Seminal colliculus and prostatic urethra

9

Identify

Q image thumb

Erectile tissue

10

Describe the distinct nuclear morphology of Sertoli cells

Round/oval nucleus with prominent nucleolus

11

Name the large cells found at or near the basement membrane of the seminiferious epithelium

What do they do?

spermatogonia

Serve as stem cells -> divide, producing a 'son' cell. The new spermatogonia (primary spermatocytes) then undergoes meiosis to form secondary spermatocytes (spermatids).

12

What two hormones are primarily responsible for spermatogenesis and spermatid maturation?

FSH and testosterone

13

What specific phosphodiesterase is encriched in the smooth muscle cells of the erectile tissues (spongiosum and cavernosum)?

What drug specifically inhibits this isoform?

PDE-5

Sildenafil (Viagra)

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