Male Path

Question 1

Kallman’s syndrome is at the level of the ___ and stops the release of ___

Answer 1

hypothalamus; GnRH

Question 2

Hyper____ by a tumor can throw the feedback mechanism out of sync

Answer 2

prolactina

Question 3

___ occurs in 1% of males and is a failure of the testes to descend. It can also result in ___ of the testes

Answer 3

Cryptorchidism; neoplasm

Question 4

A cause of infertility in cryptorchidism is a thickening of the ___ ___ in the tubules

Answer 4

basement membrane

Question 5

Germ cell sloughing is commonly caused by

Answer 5

varicoceles

Question 6

Sertoli cell only syndrome has a number of causes, the cure is __, and causes 5-10% of infertility

Answer 6

non-existent

Question 7

Seminomas are exquisitely sensitive to ___

Answer 7

radiation

Question 8

The most consistent genetic abnormality of a germ cell tumor is the ___ of the short arm of chromosome __

Answer 8

isochromosome; 12p

Question 9

All germ cell tumors begin with _____ ___ ___ ___

Answer 9

intratubular germ cell neoplasia

Question 10

Histology of seminomas- _____ (style), ___ (color), __ (size) cells with ___ infiltrate

Answer 10

homogenous; clear; large lymphocytic

Question 11

Seminomas may have slightly elevated __, but are mostly __ and __ negative

Answer 11

hCg; HCG; AFP

Question 12

Embryonal carcinomas are seen in ___ only, not __

Answer 12

young adults; kids

Question 13

Embryonal carcinoma cells are ___ (style)

Answer 13

very atypical

Question 14

Yolk sac tumors are the most common testicular tumor in ___

Answer 14

children

Question 15

Grossly, seminomas are __ and ___

Answer 15

fleshy and homogenous

Question 16

Histologically, YST have ___ ___ bodies, which are neoplastic cells surrounding a hollow core

Answer 16

schiller-duval

Question 17

YST are positive for ___

Answer 17

AFP

Question 18

Choriocarcinomas are generally ____ (size) with lots of ___

Answer 18

small; hemorrhage

Question 19

Choriocarcinomas have high levels of circulating __

Answer 19

hcG

Question 20

Two distinct age groups of teratomas- less than age _ and between _ and _ decade

Answer 20

4; 2; 4

Question 21

Adult teratomas are always ___

Answer 21

malignant