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Flashcards in Male Path Deck (21):
1

Kallman's syndrome is at the level of the ___ and stops the release of ___

hypothalamus; GnRH

2

Hyper____ by a tumor can throw the feedback mechanism out of sync

prolactina

3

___ occurs in 1% of males and is a failure of the testes to descend. It can also result in ___ of the testes

Cryptorchidism; neoplasm

4

A cause of infertility in cryptorchidism is a thickening of the ___ ___ in the tubules

basement membrane

5

Germ cell sloughing is commonly caused by

varicoceles

6

Sertoli cell only syndrome has a number of causes, the cure is __, and causes 5-10% of infertility

non-existent

7

Seminomas are exquisitely sensitive to ___

radiation

8

The most consistent genetic abnormality of a germ cell tumor is the ___ of the short arm of chromosome __

isochromosome; 12p

9

All germ cell tumors begin with _____ ___ ___ ___

intratubular germ cell neoplasia

10

Histology of seminomas- _____ (style), ___ (color), __ (size) cells with ___ infiltrate

homogenous; clear; large lymphocytic

11

Seminomas may have slightly elevated __, but are mostly __ and __ negative

hCg; HCG; AFP

12

Embryonal carcinomas are seen in ___ only, not __

young adults; kids

13

Embryonal carcinoma cells are ___ (style)

very atypical

14

Yolk sac tumors are the most common testicular tumor in ___

children

15

Grossly, seminomas are __ and ___

fleshy and homogenous

16

Histologically, YST have ___ ___ bodies, which are neoplastic cells surrounding a hollow core

schiller-duval

17

YST are positive for ___

AFP

18

Choriocarcinomas are generally ____ (size) with lots of ___

small; hemorrhage

19

Choriocarcinomas have high levels of circulating __

hcG

20

Two distinct age groups of teratomas- less than age _ and between _ and _ decade

4; 2; 4

21

Adult teratomas are always ___

malignant