Flashcards in Male Reproductive System - HY Deck (34):
The primary sex cords form the:
1. Seminiferous cords.
2. Tubuli recti.
3. Rete testes.
Seminiferous cords consist of ...?
1. Primordial germ cells.
2. Sustentacular (Sertoli) cells --> Secrete MIF.
The mesoderm between the seminiferous cords gives rise to the ...?
Interstitial (Leydig) cells --> Testosterone.
The seminiferous cords remain as solid cords until ...?
Puberty, when they acquire a lumen and are then called seminiferous tubules.
The peritoneum envaginates alongside the gubernaculum to form the ...?
Later in the development, most of the processus vaginalis is obliterated except at ...?
Its DISTAL end, which remains as a peritoneal sac called the TUNICA VAGINALIS of the testes.
The cranial portions of the paramesonephric ducts (Mullerian) run parallel to the ...?
The caudal portions of the paramesonephric ducts fuse in the midline to form the ...?
Under the influence of ..., the cranial portions of the paramesonephric ducts and the uterovaginal primordium regress.
Vestigial remnants of the paramesonephric duct (called ...) may be found in the adult male.
The mesonephric (Wolffian) ducts develop in the male as part of the ... because these ducts are critical in the formation of the definitive metanephric kidney.
The mesonephric ducts also proceed to additionally form the:
2. Ductus deferens.
3. Seminal vesicle.
4. Ejaculatory duct.
A few mesonephric tubules in the region of the testes form the ...?
Efferent ductules of the testes.
Vestigial remnants of the mesonephric duct (called the ...) may be found in the adult male.
Vestigial remnants of mesonephric tubules (called the ...) also may be found in the adult male.
The phallus forms the ...?
Penis (glans penis, corpora cavernosa penis, and corpus spongiosum penis).
The urogenital folds form the ...?
Ventral aspect of penis (ie penile raphe).
The labioscrotal swellings form the ...?
Hypospadias occurs when ...?
The urethral folds fail to fuse COMPLETELY, resulting in the external urethral orifice opening onto the VENTRAL surface of the penis.
Hypospadias is associated with a ...?
Poorly developed penis that curves VENTRALLY --> Chordee.
Epispadias occurs when ...?
The external urethral orifice opens onto the DORSAL surface of the penis.
Epispadias is generally associated with ...?
Exstrophy of the bladder.
Hydrocele of the testes occurs when ...?
A small patency of the processus vaginalis remains so that peritoneal fluid can flow into the PROCESSUS VAGINALIS.
--> Due to persistence of tunica vaginalis.
Congenital inguinal hernia occurs when?
A large patency of the processus vaginalis remains so that a loop of intestine may herniate into the scrotum or labia majora.
Congenital inguinal hernia is associated with ...?
Because the early embryo goes through an indifferent stage, events may occur whereby a fetus does not progress toward either of the two usual phenotypes, but gets caught in an intermediate stage known as ...?
Intersexuality is classified according to the ...?
Histological appearance of the gonad + ambiguous genitalia.
True intersexuality occurs when ...?
An individual has BOTH ovarian + testicular tissue (ovotestes) histologically + Ambiguous genitalia + 46XX genotype --> Rare condition.
Female pseudointersexuality occurs when ...?
An individual has only OVARIAN TISSUE histologically + Masculinization of the female external genitalia.
Female pseudointersexuality - Genotype?
FP is most often observed clinically in associated with ...?
A condition in which the fetus produces EXCESS of androgens (congenital adrenal hyperplasia CAH).
Female pseudointersexuality - Clinical findings:
1. Mild clitoral enlargement.
2. Complete labioscrotal fusion with a phalloid organ.
3. Macrogenitosomia (in male fetus).
Masculinization of the female external genitalia is apparent with ...?
Fusion of the labia majora + Enlarged clitoris.