MCB Lecture 30 Cytosol Flashcards Preview

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Flashcards in MCB Lecture 30 Cytosol Deck (28)
0

Describe the cytosol

It is the interior of the cell membrane
The cell is very crowded, so there is not much cytosol

1

Describe the membrane structure of organelles

Single lipid bilayer from the same design plan

2

Describe the design plan of organelles, and what this means for transport between them

The organelles have the same design plan. This means that one organelle can turn into another by budding and forming vesicles.

Also, transport between organelles is simple: vesicular transport

3

Extracellular space is topologically equivalent to ...

The lumen of organelles

4

Describe how molecules are transported between organelles

Budding and fusion of vesicles

5

Which organelles have two lipid Bilayers?

Nucleus, mitochrondria, chloroplasts

6

Describe the evolution of a nucleus

DNA was present in the cytosol (like prokarya), then it became surrounded by a membrane that split off from the plasma membrane

7

The nuclear intermembrane space is continuous with ...?

The rough endoplasmic reticulum

8

The nuclear innermembrane space is continuous with ...?

The cell cytosol

9

Describe the evolution of mitochondria

An aerobic bacterium was engulfed by the cell into a vesicle. It has remained in this vesicle

10

Which proteins are involved with the cytoskeleton?

Motor proteins
The structure itself, eg. actin

11

Which proteins are associated with the nucleus?

Transcription factors, spliceosome

12

Which proteins are associated with the cell membrane?

Transporters
Receptors
Channels

13

Which proteins are associated with the mitochondria?

The complexes on the inner membrane involved with the electron transport chain

14

Which proteins are associated with the endoplasmic reticulum?

Ribosomes
Translocators
Chaperones

15

Which proteins are associated with the Golgi apparatus?

Many enzymes for all the modifications that go on

16

Which proteins are associated with the lysosomes?

Lysosomal enzymes

17

Which proteins are secreted?

Eg. Insulin, collagen

18

Where does protein synthesis begin?

On a ribosome in the cytosol

19

What are the two challenges of protein trafficking?

1. Access to a compartment
2. Targeting to a compartment

20

What are the three mechanisms of transport of molecules around the cell?

1. Gated
2. Transmembrane transport
3. Vesicular transport

21

Where does gated transport occur?

Nucleus <-> cytosol

22

Where does transmembrane transport occur? What does it require?

From the cytosol to the mitochondria, peroxisomes and ER

23

Where does vesicular transport occur?

Between organelles

24

How can one organelle turn into another?

Vesicle budding and fusion

25

What does it mean when we say that a cell is functionally compartmentalised?

That areas are delineated into compartments which have different functions

26

How can one organelle turn into another?

Vesicle budding and fusion

27

What does it mean when we say that a cell is functionally compartmentalised?

That areas are delineated into compartments which have different functions

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