Measles, Mumps, Rubella, Parvovirus Flashcards Preview

Virology > Measles, Mumps, Rubella, Parvovirus > Flashcards

Flashcards in Measles, Mumps, Rubella, Parvovirus Deck (15):
1

increased severity for this viral infection w/Vitamin A deficiency

 

Measles

1

clinical manifestation of parvovirus B19

  1. erythema infectiosum - fever/malaise followed by characteristic cheek rash
  2. arthralgia - most common in women
  3. anemia
    • can become aplastic in individuals w/hemoglobinophathies(sickle cell)
    • worse for immunocompromised
  4. risk of fetal hydrops if mama is infected
    • bad for pregos to get parvo
  5. myocarditis

2

paramyxovirus causing transient, profound immunosuppression

allows for secondary infections:BAD diarrhea, pneumonia

measles

3

genomes of measles, mumps, rubella, parvovirus B19

  • measles, mumps - ssRNA(-)
  • rubella - ssRNA(+)
  • parvovirus B19 - ss/linear DNA

3

congenital rubella syndrome trifecta

cataracts

heart disease

deafness

 

"blueberry muffin" rash from BM cells; 

4

clinical manifestation of rubella

Rash(occurs w/fever) - more patchy than the confluent measles rash; moves head-->toe, disappearing in same order, a few days later

cervical lymphadenopathy

arthritis

5

complications of measles

transient immunosuppression: allows coinfections

encephalitis: acute, acute disseminated, sub acute sclerosing panencephalitis(years later)

worse if immunosuppressed, malnutritious(vit A)

6

why rubella vaccine?

can spread from mother>>child if mama is infected in first trimester and cause congenital rubella syndrome. DO IT FO DA BABIES

8

extremely small, naked, icosahedral, ssDNA virus that infects/kills bone-marrow precursor cells

parvovirus B19

9

erythema infectiosum or 5th disease

 

symptoms?

virus?

Parvovirus B19

 

initially causes mild fever, malaise, myalgia, HA

followed by "slapped-cheek rash" on face and lace-like rash on body

11

transmission for measles, mumps, rubella, parvovirus B19?

respiratory droplets is a common transmission for all

 

12

clinical features mumps

systemic disease

POM- parotiditis, orchitis(testes swelling), meningitis(Aseptic)

 

13

Slapped cheek rash

 

viral cause?

parvovirus B19

14

clinical features of measles

the 3 C's(and a k)

  • conjunctivitis
  • cough
  • coryza(runny nose)
  • Koplik's spots - enanthem; white spots in mouth; 

Rash follows the koplik's spots; starts as dots that later become confluent

15

complications of mumps

encephalitis

deafness(leading cause before vaccine)

infertility(RARE)