Megaloblastic Anaemia Flashcards Preview

A - Haematology > Megaloblastic Anaemia > Flashcards

Flashcards in Megaloblastic Anaemia Deck (3)
Loading flashcards...
1

What are megaloblastic anaemias characterised by pathologically?

Delayed maturation of the nucleus of the red cells in the bone marrow due to defective synthesis of DNA

2

What can happen to RBCs produced with delayed maturation of the nucleus?

Can die in marrow or enter bloodstream as enlarged, misshapen cells with reduced survival time

3

What causes megaloblastic anaemia?

B12 or folate deficiency