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Flashcards in Metabolic & Endocrine Disorders Deck (94)
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1

Normal bone quality, decreased bone quantity =

Osteoporosis

2

Females are affected by osteoporosis __:__ over males

4:1

(After 80, females = males)

3

Secondary causes of ____ include metastasis, multiple meyloma, alcoholism, endocrine disorders, etc. 

OSteoporosis

4

Clinical presentation of ____ include:

- Clinically silent

- Increased kyphosis as disease progresses

- Symptoms become apparent when there are fractures

Osteoporosis

5

Radiographs are ____ (good/not good) are grading osteoporosis

Not good

6

Radiographic findings of ____ include:

- Osteopenia (on radiographs this is a descriptive term ie. less dense, DEXA scan it is diagnosis)

- Loss of 2° stress trabeculae, accentuation of 1° trabeculae

- Vertical striations in VBs (pseudohemangiomas)

- Pencil thin cortices

- Compression fractures (anterior wedge, fish vertebra)

Generalized Osteoporosis

7

What are is the likely cause of these findings?

(Normal on left)

Generalized Osteoporosis - CT w/ Fish Verterbra

8

What is the likely cause of these findings?

Generalized Osteoporosis - Accentuated Vertical Striations (pseudohamangiomas)

9

What is the likely cause of these findings?

Generalized Osteoporosis - Accentuated Vertical Striations, anterior wedging, and gas bubble

10

What is the likely cause of these findings?

Generalized Osteoporosis - Anterior compression fracture as a result of hyperkyphosis

11

What is the likely cause of these findings?

Generalized Osteoporosis - Ward's Triangle

12

What is the likely cause of these findings?

Generalized Osteoporosis - Pencil thin cortices

13

What is the likely cause of these findings?

Generalized Osteoporosis - Insufficiency Fracture

14

____ is gold standard for osteoporosis diagnosis, ____ is most accurate but expensive

DEXA scan

Quantitative CT

15

____ is the most common cause of regional osteoporosis

Other causes are ___ & ____

Disuse (common following immobilization)

Complex Regional Pain Syndrome (CRPS) & Transient osteoporosis of hip (TROH)

16

Regional osteopenia can be seen within _____ in disuse regional osteoporosis, _____ following CRPS

7-10 days

3-4 months

17

What is the most likely cause of these findings?

Regional Osteoporosis - Disuse

18

- Relatively normal bone quantity, poor bone quality

- Results in soft bones

Imaging findings include: 

- Generalized osteopenia

- Trabecular coarsening & indistinctness

- Fracture deformites (fish vertebrae, Triradiate pelvis, kyphoscoliosis, etc.)

- Pseudofractures (insufficiency fractures in unusual locations)

Osteomalacia

19

What is the most likely cause of these findings?

Osteomalacia - but NOT associated specifically, can be seen in any condition with decreased bone density (quantity, quality or both)

20

What is the most likely cause of these findings?

Osteomalacia - Pseudofractures

(Can also be seen in Padgets or Fibrous dysplasia)

21

- Vitamin D related

- Primarily a disease of growth plates (seen w/ osteomalacia)

- Clinically, may see bowing deformities, overgrowth of cartilage near joints, "rachitic rosary"

Rickets

22

Image findings of ____ include:

- "Paint brush" metaphysis

- Splayed/cupping of metaphysis

- Non-calcified zone of provisional calcification → widened growth plate

Rickets

23

What is the most likely cause of these findings?

Rickets - Non-calcific zone of provisional calcification & cupped appearance

24

What is the most likely cause of these findings?

Rickets - Paint brush metaphysis

25

What is the most likely cause of these findings?

Rickets - Rachitic Rosary

26

What is the most likely cause of these findings?

Rickets - Bowing Deformities

27

What is the most likely cause of these findings?

Scurvy

28

Dense zone of provisional calcification in scurvy =

White line of Frankel/scurvy

29

Well defined ring around epiphysis seen in scurvy =

Wimberger’s ring

30

- Arise from metaphyseal margins

- Due to collapse of the scorbutic zone

- Seen in Scurvy

Pelken’s spurs