Metabolism Overview

Question 1

mTOR is a protein kinase responsible for 4 things

Answer 1

1. Protein Synth
2. Lipid Synth
3. Autophagy
4. Energy Metabolism

Make those macros,

Question 2

mTOR inhibits _____ biogenesis to avoid breaking down components

Answer 2

Lysosome

Question 3

The kinase that antagonizes the mTOR anabolic functions is ______

Answer 3

AMPK

Question 4

Excercise, Ghrelin, Adiponectin, AMP, and low O2 all promote _____ Kinase to promote catabolic funciton

Answer 4

AMP

Question 5

ATP closes ____ channels, causes a depolarization and makes Calcium enter to release insulin

Answer 5

K+

Question 6

Sulfonyl drugs bind tp ____ channels, to enhance insulin release

Answer 6

K+

Question 7

C-peptide is a good indicator of ____ insulin

Answer 7

Endogenous

Question 8

Insulin’s Tyrosine Kinase has ____-dependent signaling to alter Gene transcription and ____ signaling to alter protein and enzyme activity.

Answer 8

RAS, mTOR/AKT

Question 9

4 organs that are most insulin responsive

Answer 9

Liver, Skeletal muscle, Adipose, Brain

Question 10

Liver mainly uses GLUT___
Skeletal Muscle mainly uses GLUT____
Brain muscle uses GLUT____

Answer 10

• 2
• 4
• 3

Question 11

Glucagon and Epinephrine bind to _____ coupled receptor

Answer 11

G-protein

Question 12

Muscle has Epinephrine Receptors but not _____ Receptors

Answer 12

Glucagon

Question 13

Cortisol has a catabolic effect by breaking down _____

Answer 13

muscle