Metabolism Part 1 Flashcards

1
Q

the sum total of all chemical reactions occurring in the cell

A

metabolism

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2
Q

breakdown of larger complex molecules into smaller ones, energy is released

A

catabolism

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3
Q

the synthesis of complex molecules from simpler ones using energy

A

anabolism

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4
Q

occur as a series of chemical reactions using intermediates to convert the starting molecules to products

A

metabolic pathways

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5
Q

these make reactions of life possible at livable temperatures
also mediate the steps in metabolic pathways

A

enzymes

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6
Q

what are the enzymes doing

A

acting as catalysts

catalyze reaction by lowering activation energy

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7
Q

energy required to form transition state complex

A

activation energy

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8
Q

are enzymes consumed in reactions

A

no

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9
Q

this is the region where the substrate(s) attach

A

active site

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10
Q

enzyme conformation changes as substrates enter, closing around substrates

A

induced fit

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11
Q

how are enzymes classified

A

based on the type of chemical reaction catalyzed

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12
Q

Non protein component needed for functioning enzyme

Ex/ magnesium, zinc, copper

A

Cofactors

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13
Q

Organic cofactors
Act as carriers for molecules or electrons
Not as specific as enzymes
May act with numerous enzymes

A

Coenzymes

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14
Q

What are the three regulation

A

Non competitive inhibition
Competitive inhibition
Feedback inhibition

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15
Q

Inhibitor and substrate act on different enzyme sites

Allosteric vs feedback inhibition

A

Non competitive inhibition

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16
Q

Inhibitor competes for active site with the substrate

Inhibitor is structurally similar to the substrate

A

Competitive inhibition

17
Q

Product of a series of enzyme controlled reactions

Inhibits the first enzyme in the pathway

A

Feedback inhibition

18
Q

What is the capacity to do work

19
Q

Exists as potential and kinetic energy

Microbes use various energy sources (light, organic and inorganic molecules)

A

Harvesting energy

20
Q

This releases energy

Example is burning sugar

A

Exergonic reactions

21
Q

Use energy to produce the products

A

Endergonic reactions

22
Q

What is the currency of the cell

23
Q

Where is energy held

A

I’m high energy bonds between phosphate groups

24
Q

Production of ATP

A

1) substrate level phosphorylation
2) oxidative phosphorylation
3) photophos phorylation

25
This uses chemical energy to add phosphate ion to molecules of ADP
Substrate level phosphorylation
26
Uses energy from proton motive force to add phosphate ion to ADP
Oxidative phosphorylation
27
Utilized radiant energy from sun to convert phosphorylation ADP to ATP
Photophosphorylation
28
These are reactions in which there is a transfer of one or more electrons between reactant molecules
Oxidation reduction reactions
29
A molecule on which electrons are parked | Transport energy from one point in the cell to another
Electron carriers
30
What are the three important electron carriers
NAD+ FAD NADP+
31
What are the three key pathways
Glycolysis, pentose phosphate pathway, tricarboxcylic acid cycle
32
What are the central pathways
Catabolic
33
Pathways modify organic molecules to form what
High energy intermediates to synthesize ATP intermediates to generate reducing power Intermediates and end products as precursor metabolites
34
What is glycolysis also called
Embden myerhoff pathway
35
In general what does glycolysis do
Oxidizes glucose to two molecules of pyruvate
36
What are the two phases of glycolysis
Preparation and energy harvest
37
During this add two phosphates from ATP to 6 carbon sugar | I’m bacteria, first ATP added during group transports through membrane
Preparation
38
Two 3C molecules rearranged to pyruvate | Each produces 2 ATP and 1 NADH
Energy harvest