Metabolism Pathogens 1 Flashcards
Streptococcus pyogens is gram stain?
Gram (+) ; cocci
Streptococcus pyogenes causes ?
Strep throat, scarlet fever, Rheumatic fever, necrotizing fasciitis
Streptococcus pyogenes pathogenesis
Displays M protein
- aids in colonization
- antiphagocytic ( protein will not allow to be phagocotized )
Hyaluronic acid capsule (glue connective tissue )
- helps evade immune system
- resist phagocytosis
Produces exoenxymes:
- streptokinase : break down clots attempting to isolate streptococcus pyogenes
- hyaluronidase: hydrolyzes hylauronic acid
Strep throat transmission
Droplet
Strep throat signs/symptoms
Fever, sore throat, tonislitis, enlarged lymph nodes
Scarlet fever transmission
Droplet
Progress from strep throat (untreated)
What does streptococcus pyogenes produce in scarlet fever ?
Erythogenic toxin -> pink/red skin rash
Scarlet fever signs
Skin rash
Spotted, strawberry-like tongue
Rheumatic fever transmission
Autoimmune complication
-mis directed immune reaction againt M protein
Rheumatic fever signs/symptoms
Arthritis
-nodules at joints
Fever
Inflammation of heart
Necrotizing fasciitis is
Flesh eating bacteria
Necrotizing fasciitis transmission ?
Streptococcus pyogens enters through breaks in skin
Streptococcus pyogens produce ?
Toxins that destory tissue
Spread quickly
Streptococcus pyogenes dx
Culture
Detection of streptococcus pyogenes antigen test
Streptococcus pyogenes tx
Penicillins or cephalosporins
