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Flashcards in Micro Final Details Deck (37):
1

Action of the diptheria and pseudomonas exotoxin A

Robosylate and inactivate EF-2 (AB-toxin)

2

Action of pertussis toxin

Inactivated Gi--> increased cAMP

Impairs phagocytosis

3

Cleaves snare proteins, inhibiting the release of neurotransmitters

Botlinum (prevent Ach release) and tetnus toxin (prevents GABA relase)

4

Phospholipase that degrades cell membranes

C. perfringings Alpha Toxin

5

mechanism of streptolysin O toxin

Lyses RBC

6

Approximate MHC-II and T-cell receptors resulting in overwhelming release of INF-y and IL-2

S. pyogenes exotoxin A

S. aureus TSST-1

7

ability to take up naked DNA from the environment and incorporate it into it's own genome

Transformation

8

Phage DNA incorportated into bacterial chromosome

Generalized tranduction

9

Bacterial DNA accidentally incorporated into viral genome when it is excized

Specialized transduction

10

G (+) Rods

Clostridium (anaerobe) (Cant Breath Air)

Corynebacterium

Listeria

Bacillus (aerobe) (Nagging Pests Must Breath)

Mycobacterium (acid fast)

11

Binds Fc of IgG preventing complement formation

S. aureus

Protein A

12

Lancet shaped diplococci with an IgA protease

S. pneumonia

Optochin sensitive

13

G(+) rods with metachromatic granules

C. diptheriae

14

Location of GABA inhibition by tetanus toxin

Inhibits SNAREs in the Renshaw cells of the GABAercic

neurons of the spinal cord

15

Drug most commonly responsible for psuedomembranous colitis

Clindamycin and ampicillin

16

Tumbling G(+) rod

Tx?

Listeria

Ampicillin

17

Primary TB

Gohn focus (mid zone)

Hilar lymphadenopathy

-->Gohn complex

18

2' TB

Fibrocaseous necrotic lesion in upper lobes

19

Two virulence factors of mycobacterium

Cord Factor: Inhibits macrophage matuation and induces TNF-alpha release

Sulfatide: Surface glycolipid which inhibits lysosomal fusion (reason why they can live inside macrophages)

20

Leprosy infection with poor Th1 response?

Strong Th1 response?

Poor Th1: Lepromatous--> diffuse and communicable

Stong Th1: Tuberculoid: hypoesthtic nodues and hairless plaques

21

G(-) Rod, Lactose nonfrementer, Oxidase (-)

Shigella

Salmonella

Proteus

22

Culture difference between salmonella and shigella?

Salmonella--> motile H2S (+)

Shigella--> NON-motile H2S (-)

23

G(-) Rod lactose fermenters

E. coli

Klebsiella

 

24

Culture difference between klebsiella and E.coli

E. coli Indole (+)

Klebsiella Indole (-)

25

Vaccine for this bug contains capsular polysaccharide (polyribosylribitol phosphate) conjucated to diptheria toxoid

H. influensza

26

E. coli infection that is fecal leukocyte (+)

EIEC

27

Bloody diarrhea and sorbitol non-fermenter

EHEC (O157:H7)

28

rose spots on abdomen, fever and diarrhea

Typhoid fever

Salmonella typhi

29

Spirochete visualized on giesma of wright stain

Borellia

(Treponema is too small)

30

Obligate intracellular organism that needs CoA and NAD+

Rickettsia sp.

31

Centrifugal rash sparing the palms and soles

R. prowazekii--> enpidemic typhus--> human louse

32

monocytes with berry-like inclusions

Ehlichiosis

33

Cell wall lacking muramic acid

Chlamydia

34

Follicular conjuctivits chlamydia types

A, B, C

Causes blindiness in africa

African Blindness Chlamydia

35

Types of chlmydia that cause PID and Urethritis

types D-K

Sexually transmitted...D-K...Think about it.

36

Lymphgrnauloma venereum

Painful lyphadenitis and ulceration

Chlamydia L1, L2 and L3

37

Anemia with pneumonia

M. pneumoniae

Cold agglutinins--> IgM binds to RBC in periphery--> lysed in spleen

Anemia resolves wheni infection is Tx'ed