Microbilogy Chapter 20 antimicrobial drugs Flashcards Preview

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Flashcards in Microbilogy Chapter 20 antimicrobial drugs Deck (20):
1

Definition: Chemicals to cure.

Chemotherapy

2

Act by killing or interfering with the growth of microbes within a host

Antimicrobial drugs

3

A substance produceded by microbe that, in small amounts, inhibits another microbe

Antibiotic

4

Kills the microbe and not affect the host.

Selective Toxicity

5

Only kills 1 species.

Narrow spectrum

6

Kills multiple types of microbes

Broad spectrum

7

When antibiotic therapy kills normal flora. This can happen.

Superinfection

8

The lack of resistance to antimicrobials

Bacterial susceptibility

9

The ability to resist antimicrobial agents

Bacterial resistance

10

Microorganisms present in or on host

Normal Flora

11

Kill Bacteria

Bactericidal

12

Inhibit growth of bacteria

Bacteriostatic

13

Wanted to create "Magic Bullets". Sularsan. Arsenaginic compound.

Paul Ehrlich

14

Developed sulfa drugs. Sulfanilamide. Also discovered simisynthetic drugs and synthetic drugs.

Gerhard Domagk

15

Why is it harder to kill gram negative microbes?

More complex cell wall.

16

Have a B-lactum ring

Penicillin

17

Treatment used for penicillin

-Oral
-Intramuscular

18

Susceptibility to Penicillases also known as ________

B-Lactamase

19

How do Penicillins work?

Attack bridges in the cell wall which destroys the cell.

20

Blocks secretion of NAG and NAM from cytoplasm.

Bacitracin