MicroBioFinal - LymeDisease Flashcards Preview

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Flashcards in MicroBioFinal - LymeDisease Deck (7)
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1

disease agent

Barrelia Burgdorferi (underlined)
- spirochete
- gram negative
- motile (flagella)
- 40% plasmid dna
- binary fission

2

transmission

biological vector: black legged tick(deer tick)
- must bite for atleast 48 hrs to transmit bacteria
- CDC says it cannot be transmitted through sexual activity
- replication occurs in bone, tendon, nerves, joints, etc.

3

symptoms

3 week incubation
- early localized - target lesions, stiff neck
- early disseminated - several weeks; systemic; multiple target lesions, cardiac problems, neurological problems, etc.
- late lyme - joint problems, cardiac problems, neuropathies, etc

4

detection

- early localized - target lesion
- early disseminated - look for seroconversion (lyme antibodies)
- late lyme - need dna fingerprint at this point

5

treatment

- early localized - Doxycycline: 21 days; attacks ribosomes; Amoxicilin: if pregnant; 21 days; attacks cell wall production
- early disseminated - therapies that depend on symptoms
- late lyme - therapies and Doxycline and Amoxicillin; 1 month

6

prevention

- Lymerix Vaccine - actually gave ppl lyme disease; used from 1998-2002
- protective clothing
- deet, teatree oil, natural herbs
- public awareness; check for ticks

7

epidemiology

tick: 2 yr life cycle
- lyme typically spread may, june, july
- early localized and disseminated found in august, september, october