*Microbiology 5 (antibiotic man/ antibiotics given for what) Flashcards Preview

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Flashcards in *Microbiology 5 (antibiotic man/ antibiotics given for what) Deck (46):
1

Treatment of mild CAP?

Oral Amoxicillin

2

Treatment of mild CAP if penicillin allergy?

Oral Doxycycline

3

Treatment of moderate CAP?

IV Amoxicillin

4

Treatment of moderate CAP if penicillin allergy?

IV clarithromycin

5

Treatment of severe CAP?

Co-amoxiclav IV + either Clarithromycin IV or doxycycline oral
Step down to doxycycline

6

Treatment of severe CAP if penicillin allergy?

IV Levofloxacin
Step down to doxycycline

7

Treatment of severe HAP/ aspiration pneumonia?

IV amoxicillin + metronidazole + gentamicin
Step down to co-trimoxazole + metronidazole

8

Treatment of severe HAP/ aspiration pneumonia if penicillin allergic?

IV co-trimoxazole + metronidazole + gentamicin
Step down to co-trimoxazole + metronidazole

9

Treatment of non-severe HAP/ aspiration pneumonia if penicillin allergic?

oral co-trimoxazole + metronidazole

10

1st and 2nd line treatment for acute exacerbation of COPD?

1st line = amoxicillin
2nd line = doxycycline

11

Treatment for endocarditis (native valve indolent (Subacute))?

Amoxicillin IV + gentamicin IV

12

Treatment for endocarditis? (native valve severe sepsis (acute))

Flucloxacillin IV

13

Treatment for endocarditis? (prosthetic valve or suspected MRSA)

Vancomycin IV + Rifampicin oral + gentamicin IV

14

Treatment for endocarditis? (native valve severe sepsis + risk factors for resistant pathogens)

Vancomycin IV + Meropenem IV

15

Treatment of non-severe C. diff. infection?

Oral metronidazole

16

Treatment of severe C. diff.?

IV vancomycin +/- IV metronidazole

17

Treatment of peritonitis/ biliary tree infection/ intra-abdominal infection?

IV amoxicillin + metronidazole + gentamicin
Step down to oral Co-trimoxazole + metronidazole

18

Treatment of peritonitis/ biliary tree infection/ intra-abdominal infection if allergic to penicillin?

IV vancomycin + metronidazole + gentamicin
Step down to oral Co-trimoxazole + metronidazole

19

Antibiotics for acute gastroenteritis?

No antibiotic treatment recommended

20

Antibiotics for acute pancreatitis?

Antibiotic treatment does not improve outcome?

21

Treatment for severe proven spontaneous bacterial peritonitis?

Pipercillin/ Tazobactam IV ("Tazocin")
Step down to oral co-trimoxazole

22

Treatment for mild proven spontaneous bacterial peritonitis?

Oral co-trimoxazole

23

Treatment of a streptococcus throat infection?

Penicillin

24

Treatment of a gas gangrene clostridium infection?

metronidazole + penicillin

25

What is the first line treatment for staph. aureus infection?

Flucloxacillin

26

Treatment of staph. and strep. skin and soft tissue infection?

Flucloxacillin

27

Treatment of urinary sepsis/ pyelonephritis in hospital?

Amoxicillin and gentamicin

28

Treatment of pyrexia of unknown origin?

Amoxicillin + gentamicin + metronidazole

29

What 3 bacteria can co-amoxiclav not treat?

MRSA
Pseudomonas sp.
Resistant coliforms

30

What is used to treat pyelonephritis in the community?

Co-amoxiclav

31

How are the atypical pneumonias treated?

Clarithromycin, Ciprofloxacin

32

What antibiotics can be used to treat MRSA?

Vancomycin, Gentamicin

33

What antibiotic is used to treat co-agulase negative staph infection in a prosthetic limb?

Vancomycin

34

How long is gentamicin usually prescribed for?
Why must patients on gentamicin have their blood levels monitored?

3 days
Gentamicin toxicity can cause damage to CNVIII (deafness and dizziness) and kidneys

35

What drug is given for protozoal infections?

Metronidazole

36

What antibiotic is given for material vaginosis?

Metronidazole

37

What are 3 problems with metronidazole?

It is not recommended during the first trimester of pregnancy
It can give a nasty metallic taste in the mouth
It interacts badly with alcohol

38

What is the only oral antibiotic that has activity against pseudomonas sp?

Ciprofloxacin

39

What antibiotic is used to treat UTIs?

Trimethoprim

40

What problem can sulphamethoxazole cause?

Rarely Steven-Johnson syndrome - a severe skin reaction

41

What problem can doxycycline cause?

Brown staining of the teeth in children

42

What is used to treat gonnorhoea

Ceftriaxone (given IM)

43

What is used to treat bacterial meningitis?

Ceftriaxone (IV)

44

What drug (in very general terms) is used to treat gram positive bacteria?

Amoxicillin

45

What drug (in very general terms) is used to treat gram negative bacteria?

Gentamicin

46

What drug is used to treat anaerobic bacteria?

Metronidazole