Microbiology: Antibiotic Resistance Flashcards Preview

Microbiology and Hematology > Microbiology: Antibiotic Resistance > Flashcards

Flashcards in Microbiology: Antibiotic Resistance Deck (8)
Loading flashcards...
1
Q

There are many forms of resistance and different organisms can resist _______ of some agents in different ways.

A

Activity

2
Q

Bacteria have a large rapidly multiplying population. How does this help them become antibiotic resistant?

A
  • mutations occur
  • some will develop resistance and its growth will be favored
  • can pass resistance via plasmids and conjugation
3
Q

What are the different resistance mechanisms?

A
  1. Prevent entrance of drug
  2. Pump agent out of cell
  3. Inactivate drug
4
Q

Penicillin G cannot pass through the outer membrane of ____ organisms.

A

G(-)

5
Q

What organisms can prevent entrance of drugs?

A
  • G(-) with penicillin g

- mycobacteria (glycocalyx)

6
Q

What organisms can pump an agent out of its cell?

A
  • E. coli
  • pseudomonas
  • S. aureus
7
Q

What enzyme can split penicillin molecules and inactivate it?

A

Penicillinase

8
Q

What are the things you can do to combat resistance?

A
  1. Use high enough dose of drug and soon enough do not allow time to develop resistance
  2. Continue therapy after symptoms have subsided
  3. Use a combination of drugs to lower probability that organisms can develop two or more resistances