Microbiology - Zoonoses Flashcards Preview

MS 2 - Unit 2 > Microbiology - Zoonoses > Flashcards

Flashcards in Microbiology - Zoonoses Deck (31):
1

Does the following have a vector?
Bacillus anthracis

Not usually, spores are in the dirt
infected cow can be a vector
cause of anthrax

2

Does the following have a vector?
Francisella tularensis

Causes tularemia
vectors are ticks (dermacentor tick), mosquitos, deer flies
reservoir is rabbit

3

Does the following have a vector?
Brucella species

No
Cause of brucellosis
reservoir is all farm animals, EW

4

Does the following have a vector?
Bartonella henselae

Cause of cat scratch fever
vector is flea, tick

5

Does the following have a vector?
Yersinia pestis

Cause of bubonic plague
Vector is the flea
reservoir is rodent

6

What are the three kinds of anthrax?

Cutaneous (painless black eschar),
gastronintestinal,
pulmonary

7

What is the treatment for anthrax?

Cipro (fluoroquinolones - BSA)
Doxy

8

What kind of organism is Francisella tularensis?

Cause of tularemia (type A for America more virulent than type B which is in Europe)
gram -
aerobic
coccobacilli
facultative intracellular

9

What kind of organism is Bacillus anthracis?

rods (in chains) *** very unique
obligate aerobe
spore-forming
gram +
encapsulated - unique bc made of PROTEIN (poly-D glutamic acid)

10

What toxins does anthrax have?

EF and LF
edema factor - elevation in cAMP
lethal factor - tissue necrosis

11

What are the worst outcomes from anthrax?

Widened mediastinum on x ray - pulmonary anthrax
pulmonary hemorrhage
has almost 100% mortality

12

What is "wool sorters disease"

pulmonary anthrax
people handling wool inhale spores

13

What is the most severe form or tularemia?

Pneumonic tularemia
inhaling the bacteria is during landscaping

14

what are the main symptoms of tularemia?

Regional lymphadenopathy
granulomas with caseating necrosis
painful ulcer at infection site

15

Treat tularemia with:

Aminoglycosides

16

Undulant fever is a characteristic sign of what zoonotic disease?

Brucellosis

17

What kind of bacteria is Brucella?

gram negative
facultative intracellular

18

Chronic brucellosis is characterized by what sequela?

Osteomyelitis
Hepatosplenomegaly

19

Treat Brucellosis with:

Doxy (tetracyclines)
rifampin as adjunctive therapy WITH doxy

20

What kind of bacteria is Bartonella henselae?

gram -
need a special silver stain to visualize - "Warthin-Starry" stain

21

What symptom, besides a scratch from a cat and a fever, clues you in to infection with Bartonella henselae?

Axillary lymphadenitis

22

The "version" of cat scratch fever that occurs in immunocomprimised patients (ie HIV), is actually called:

Bacillary angiomatosis
Red lesions everywhere - looks like Kaposi's

23

Treat Bartonella henselae infection with:

Doxy
Macrolides for bacillary angiomatosis

24

Infection by Pasteurella multocida is most by:

cat bites
can also be dog bites

25

Infection by Capnocytophaga canis is mostly by:

dog bites
can also be cat bites

Facultatively anaerobic gram-negative rod, part of normal oral flora of dogs and cats

26

What is the diagnosis?
Incubation period typically 1 - 6 days
History of exposure to rodents, fleas, wild rabbits, sick or dead carnivores, or patients with pneumonic plague

Plague
Yersinia pestis
*acral necrosis*

Bubonic (> 80% of presentations)
rapid onset of fever and painful, swollen, tender lymph nodes - usually inguinal, axillary, or cervical

Pneumonic
high fever, overwhelming pneumonia, cough, bloody sputum, chills

Septicemic
fever, prostration, hemorrhagic or thrombotic phenomena, acral gangrene

27

Treat plague with:

Streptomycin

28

How do people get infected with leptospira?

Contaminated water - shed in urine of animal reservoir

Acute febrile illness followed by either more mild, self- limiting symptoms or severe multiorgan involvement

29

What is the likely culprit of these symptoms?
Phase 2: (delayed, immune)
New or continued growth of bacteria in organs causes more severe symptoms
Liver: jaundice
Kidneys: renal failure
Lungs: hemorrhage
CNS: aseptic meningitis
Vascular system overall: HUS, DIC, thrombotic thrombocytopenic purpura (TTP), vasculitis

Leptospira

30

Conjunctivitis/uveitis and exposure to contaminated water source make you think of:

Leptospirosis

31

Treat leptospira infection with:

Penicillin G