Flashcards in Microcytic anaemia Deck (8)
what are the causes of microcytic anaemia?
- iron def (blood loss, dec absorption, inc demand, dec intake)
- sideroblastic anaemia (abnormal haem synthesis inherited or secondary to alcohol/drugs)
- lead poisoning
what are the presenting symptoms?
- non-specific: tiredness, lethargy, malaise, dyspnoea, pallor
- lead poisoning: anorexia, N&V, abdo pain, constipation, peripheral nerve lesions
what are the signs of microcytic anaemia?
- anaemia signs: pallor, brittle nails/hair, koilonychia
- angular stomatitis
- lead poisoning signs (blue gum line, peripheral nerve lesions, reduced consciousness, encephalopathy, convulsions)
what investigations should you do?
- FBC = iron def (low serum iron, high total iron binding capacity, low serum ferritin)
- blood film
how does iron deficiency appear on a blood film?
how does sideroblastic anaemia appear on a blood film?
- dimorphic blood film
- ring sideroblasts in bone marrow
how does lead poisoning appear on a blood film?