Flashcards in "Microscopic Anatomy Urinary System Ira Ames" 4/10 Deck (19):
List 2 hormones produced in the kidney.
Produces renin (influences fluid & electrolyte balance and blood pressure)
Produces erythropoietin (promotes rbc formation)
How would define a renal lobe?
renal pyramid plus cortical tissue overlying its base and covering its sides
The projection of each medullary pyramid into the lumen of a minor calyx is called:
What components of a nephron are contained within a medullary ray?
Collecting tubules and collecting ducts
Medullary ray is medullary tissue that projects up into the cortex.
Straight portion of PCT enters the medullary ray.
What is normally contained within the urinary space?
Urinary space is the part between the Bowman's capsule and the glomerulus
Glomerular filtrate flows through here.
Which component of the nephron begins at the urinary pole of Bowman's capsule?
What are the 3 components of the kidney filtration barrier?
1. Endothelium of glomerular capillaries fenestrated no diaphragms blocks blood cells & platelets
2. Basement membrane fusion product made by both endothelium & podocytes restricts large proteins
3. Filtration slits
What specialization of the apical surface of the epithelium lining the proximal tubules creates the brush border?
Microvilli, only found in the PCT
In which parts of the nephron are intercellular boundaries between epithelial cells not visible with the light microscope?
PCT AND DCT
List the 3 parts of the loop of Henle.
2. thin (both descending and ascending)
NOTE that a cross section of the thin limb resembles a cross section of a large capillary or small venule
What are the distinguishing morphological features of the macula densa?
(modified epithelial cells in the wall of the distal tubule)
columnar epith. nuclei close together
Found next to Bowman's capsule
Which type of nephron has the longest thin segments of the loop of Henle?
most important in the production of hypertonic urine
The visceral layer of the glomerulus has what special kinds of cells?
How is urine collected?
Collecting tubules merge to form collecting ducts which open into the minor calyx.
How can you tell the difference between a collecting tubule and a PCT?
Visible and obvious intercellular boundaries in collecting tubules
What is the diff between collecting tubule and collecting duct?
Duct - columnar epi
Tubule - cuboidal epi
What are the components of the juxtaglomerular appartus?
Macula densa (blood osmolarity and volume sensing element)
Extraglomerular mesangial cells aka Lacis cells
Juxtaglomerular cells (produce renin)
What are juxtaglomerular cells?
Modified smooth muscle cells in the tunica media of the afferent arteriole.