Microstructure Flashcards

1
Q

what characteristics do we group neurons by

A

shape
electrical activity
gene expression profile
neurotransmitter
connectivity

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2
Q

how many neurons

A

86 million

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3
Q

6 layers of neurons

A
  1. molecular layer
  2. external granular layer
  3. external pyramidal layer
  4. internal granular layer
  5. internal pyramidal layer
  6. multiform layer (layer of polymorphic cells)
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4
Q

role of pyramidal cells

A

transform synaptic inputs into a patterned output of action potentials
Involved with movement
Big amount of
Electrical information

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5
Q

axon hillock

A

regulates what proteins go in and out axons

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6
Q

telodendia

A

the terminal branches of an axon;

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7
Q

axons

A

portion of a nerve cell (neuron) that carries nerve impulses away from the cell bod

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8
Q

cell body

A

the compact section of a nerve cell that contains the nucleus and the cytoplasm

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9
Q

dendrite

A

Dendrites receive the data or signals from another neuron

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10
Q

how can we visualise neurons

A

dye into neon - fills cells = see shape

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11
Q

Oligodendrocytes

A

provide myelin sheath around neurons
structural network

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12
Q

microglia

A

immune cells in brain
remove cell debris, wastes and pathogens by phagocytosis

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13
Q

astrocytes

A

regulate neuronal functions
maintain BBB
structural support
regulate ion nitrate and gases
recoil neurotransmitters
form scar tissue after injury

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14
Q

ependymal cells

A

secrete CSF
line ventricles in brain
and spinal cord

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15
Q

Role of Glia cells

A
  • glue of NS
  • trophic support
  • regulate electrical activity
  • protect neurons from external factors
  • regulate neurotransmitter recycling
  • release gliotransmitters (ATP and D serine)
  • Ensheath synapses
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16
Q

tripartite synapse

A
  1. presynaptic terminal nerve
  2. postsynaptic spine
  3. Glial cells
17
Q

satellite cells

A

surround neuon cell bodies in ganglia
regulate o2, co2, nutrient and neurotransmitter

18
Q

Schwann cells

A

surround axons in PNS
myelination of peripheral ions
repair process after injury

19
Q

what is synaptic pruning

A

microglia change synapse number by pruning
change response to neurons
regulate firing of cells