Midterm II -- Ch. 12 - The Cell Cycle Flashcards

1
Q

cell division

A

reproduction of cells

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2
Q

cell cycle

A

the life of a cell from the time it is first formed from a dividing parent cell until its own division into two daughter cells.

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3
Q

genome

A

cell’s genetic information.

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4
Q

chromosomes

A

packages carrying genetic material (DNA molecules);

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5
Q

chromatin

A

complex DNA and proteins that makes up eukaryotic chromosomes.

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6
Q

sister chromatids

A

2 joined copies of a duplicated chromosome.

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7
Q

centromere

A

the region on each sister chromatid where they are most closely attached to each other by proteins that bind to specific DNA sequences.

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8
Q

somatic cells

A

all body cells except the reproductive cells.

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9
Q

gametes

A

sperm and eggs in reproductive cells.

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10
Q

mitosis

A

division of genetic material in the nucleus.

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11
Q

cytokinesis

A

division of the cytoplasm.

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12
Q

mitotic (M) phase

A

phase of cell cycle that include mitosis and cytokinesis.

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13
Q

interphase

A

dividing cell grows and copies its chromosomes in preparation for cell division.

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14
Q

prophase

A

1st stage of mitosis; chromatin condenses into discrete chromosome, mitotic spindle begins to form, nucleolus disappears.

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15
Q

prometaphase

A

2nd stage of mitosis: nuclear envelope fragments and spindle microtubules attach to the kinetochores of the chromosome.

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16
Q

metaphase

A

3rd stage of mitosis: spindle is complete and chromosomes are attached at the metaphase plate.

17
Q

anaphase

A

4th stage in mitosis:chromatids of each chromosome have separated and the daughter chromosomes are moving to the poles of the cell.

18
Q

telophase

A

5th (and final) stage of mitosis: daughter nuclei are forming and cytokinesis has begun.

19
Q

mitotic spindle

A

assemblage of microtubules and associated proteins that is involved in the movement of chromosomes during mitosis.

20
Q

centrosome

A

functions throughout the cell cycle to organize the cell’s microtubules.

21
Q

aster

A

radial array of short microtubules that extends from sac centrosome toward the plasma membrane.

22
Q

kinetochore

A

structure of proteins attached to the centromere that links each sister chromatid to the mitotic spindle.

23
Q

metaphase plate

A

(imaginary) structure located at a plane midway between the two poles of a cell in metaphase on which the centromeres of all the duplicated chromosomes are located

24
Q

cleavage

A

process of cytokinesis, characterized by pinching of the plasma membrane.

25
Q

cleavage furrow

A

first sign of cleavage; a small groove around the cell in the surface near the old metaphase plate.

26
Q

cell plate

A

membrane-bounded, flattened sac located at the midline of a dividing plant cell; new cell wall forms during cytokinesis.

27
Q

binary fission

A

asexual production by “division in half;”

28
Q

origin of replication

A

site where the replication of a DNA molecule begins, consisting of a specific sequence of nucleotides.

29
Q

cell cycle control system

A

a cyclically operating set of molecules in the eukaryotic cell that triggers and coordinated key events in the cell cycle.

30
Q

G0 phase

A

a non-dividing state occupied by cells that have left the cell cycle.

31
Q

cyclin

A

cellular protein that occurs in cyclically fluctuating concentration and that plays an important role in regulating the cell cycle.

32
Q

density-dependent inhibition

A

phenomenon in normal animals cells that causes them to stop dividing when they come into contact with one another.

33
Q

anchorage dependence

A

the requirement that a cell must be attached to a substratum in order to initiate cell division.

34
Q

transformation

A

process that converts a normal cell into a cancer cell.

35
Q

benign tumor

A

a mass of abnormal cells that have too few genetic and cellular changes to survive at another site; stay at original site.

36
Q

malignant tumor

A

cells whose genetic and cellular changes enable them to spread to new tissues and impair the functions of one or more organs; cancer.

37
Q

metastasis

A

spread of cancer cells to locations distant from their original site; dangerous.