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Flashcards in Misc Uworld Deck (50)
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1

niacin deficiency

pellagra

diarrhea
dermatitis
dementia
death

can be seen in people with bowel disease, vitamin absorption problems

2

pyridoxine deficiency

B6

irritability
depression
dermatitis
stomatitis

also increased serum homocysteine concentration --> thromboembolic disease, atherosclerosis

3

deficiency of cyanocobalamin

vitamin B12

macrocytic anemia and peripheral neuropathy

4

deficiency of riboflavin

B2 --> chilosis, glossitis, seborrheic dermatitis (often genital area), pharyngitis, and edema/ erythema of the mouth

5

intussusception following viral illness thought to be caused by.

hypertrophied Peyer patches

6

tricuspid valve atresia

cyanotic infant with left axis deviation, decreased pulmonary markings on x-ray

associated ASD/ AVD necessary for survival

7

hirschsprung goes with

down syndrome

8

primary amenorrhea. U/s shows presence of uterus, what's next?

test serum FSH to determine hypothalamic/ pituitary vs gonadal (peripheral) abnormalities

decreased FSH indicates central cause

9

ANA goes with

lupus

10

RF goes with

RA

11

anti CCP antibodies goes with

RA

12

ds DNA antibodies goes with

lupus and lupus nephritis

13

anti histone goes with

drug induced lupus

14

anti centromere goes with

scleroderma, CREST

15

topoisomerase antibodies goes with

scleroderma

16

mitochondrial antibodies goes with

Primary biliary cirrhosis

17

anti smooth muscle antibodies goes with

AI hepatitis

18

best tests for lupus

anti Smith and anti ds DNA

19

biggest concern with long term steroid use

osteoporosis

20

people with RA as part of perioperative testing require

x-ray of neck
(before intubation check C1-C2)

21

before starting a biologic (like rituximab) check

PPD

22

what to do for acute kidney injury with scleroderma

ACE inhibitor (usually not for AKI but in this case yes)

23

ankylosing spondylitis with new onset back pain after lifting. What to do?

x-ray to look for occult fracture

24

labs in Paget's disease

elevated alk phos and bone turnover markers (PINP, urine hydroxyproline)

normal calciuma nd phosphorus

25

secondary causes of gout

increased urate production:
myelo/ lympho prolierative disorders (like polycythemia vera)
tumor lysis
HGPT deficiency

decreased clearance:
CKD
thiazide/ loop diuretics

26

most common cause of asymptomatic elevated alk phos

paget's

27

enthesitis

pain / tenderness/ swelling where tendons insert
goes with sponyloarthropathies

28

low MCV with high iron, what do we need to do?

sideroblastic anemia; get a bone marrow biopsy

29

low MCV with normal iron, ferritin, etc. What next?

hemoglobin electrophoresis to look at thallasemias

30

everyone with sickle cell needs to take

folate