MOA by class Flashcards Preview

Pharm test #3 > MOA by class > Flashcards

Flashcards in MOA by class Deck (15):
1

Penicillins MOA

Bind PBP- inhibit crosslinking

2

aminoglycosides MOA

Irreversibly bind 30S - inhibit protein synthesis

3

cephalosporins MOA

bind PBP - inhibit crosslinking

4

Monobactam MOA

Binds PBP-3 - inhibits crosslinking

5

glycopeptides MOA

bind D-ala D-ala

6

oxazolidinones MOA

bind 50S

7

carbapenems MOA

bind PBP-2

8

lipopeptides (daptomycin) MOA

membrane depolarization - inhibits DNA and protein synthesis

9

tetracyclines MOA

reversibily bind 30S

10

TMP-SMX MOA

inhibits PABA pathway - inhibits purine synthesis

11

fluoroquinolones MOA

inhibits topoisomerases II (DNA gyrase) and topoisomerase IV

12

metronizole MOA

inhibits DNA synthesis in Anaerobes

13

clindamycin MOA

Binds 50S

14

macrolides MOA

Bind 50S

15

streptogramins MOA

bind 50S