Module 11 Flashcards

1
Q

what is a microbiome/microbiota

A
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2
Q

What are the major bacterial genera at different body sites

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3
Q

Describe the microbiota of the stomach and small intestine

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4
Q

Describe the microbiota of the large intestine

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5
Q

Describe the major components and functions of the gut microbiome

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6
Q

What are the products of intestinal microbiota and their importance

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7
Q

What are the microenvironments of the respiratory tract and their associated microbes

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8
Q

What are the factors affecting oral microbiome? How does this affect gut health?

A
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9
Q

Explain the microbiata of teeth and bacteria causing dental caries and periodontitis

A
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10
Q

What is Koch’s postulates and molecular Koch’s postulates

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11
Q

What is virulence

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12
Q

How can virulence be measured? (LD50)

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13
Q

What are the pathogen entry points

A
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14
Q

What are the pathogen exit points

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15
Q

What are the steps in infection and disease

A

Infection becomes a disease when a microorganism that is established and growing in a host causes damage and injury that impairs function

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16
Q

Explain adherence in infection

17
Q

How do pathogens adhere to hosts using specific receptor molecules

18
Q

Why does Neisseria gonorrhoeae adhere only to mucosal epithelial cells in the genitourinary tract, eye, rectum and throat

19
Q

Describe colonization

20
Q

Explain bacterial adherence and colonization of dental caries

21
Q

Explain invasion and the virulence factors that enhance colonization

22
Q

What are the virulence factors in salmonella (salmonella pathogenicity islands)

23
Q

How do enzymes function as virulence factors

24
Q

Explain streptokinase and coagulase as defense mechanisms of S. pyogenes and S. aureus

25
Describe hyaluronidase as a virulence factor
26
How does H. pylori invade stomach tissues
27
What are exotoxins (proteinacious toxin)
28
What are cytolytic (cytotoxins) exotoxins
29
What are the types of membrane disruption toxins and their functions
30
What are A-B exotoxins and their functions
31
What is the difference between the mode of action of cytotoxins and AB toxins
32
How does the diphtheria toxin block protein synthesis
33
What are botulinum and tetanus toxins
34
What is the mode of action of Botulinum and tetanus toxins
35
What are enterotoxins
36
What are superantigens
37
What are endotoxins
38
Explain virulence factors for survival in the host and immune evasion