Module 11 Flashcards
what is a microbiome/microbiota
What are the major bacterial genera at different body sites
Describe the microbiota of the stomach and small intestine
Describe the microbiota of the large intestine
Describe the major components and functions of the gut microbiome
What are the products of intestinal microbiota and their importance
What are the microenvironments of the respiratory tract and their associated microbes
What are the factors affecting oral microbiome? How does this affect gut health?
Explain the microbiata of teeth and bacteria causing dental caries and periodontitis
What is Koch’s postulates and molecular Koch’s postulates
What is virulence
How can virulence be measured? (LD50)
What are the pathogen entry points
What are the pathogen exit points
What are the steps in infection and disease
Infection becomes a disease when a microorganism that is established and growing in a host causes damage and injury that impairs function
Explain adherence in infection
How do pathogens adhere to hosts using specific receptor molecules
Why does Neisseria gonorrhoeae adhere only to mucosal epithelial cells in the genitourinary tract, eye, rectum and throat
Describe colonization
Explain bacterial adherence and colonization of dental caries
Explain invasion and the virulence factors that enhance colonization
What are the virulence factors in salmonella (salmonella pathogenicity islands)
How do enzymes function as virulence factors
Explain streptokinase and coagulase as defense mechanisms of S. pyogenes and S. aureus