1
Q
How are Macrocytic-Normochromic Anemias characterized?
A
- It is characterized by nusually large stem cells (megaloblasts) in the marrow. These cells mature into erythrocytes that are unusually large in size (macrocytic), thickness, and volume
2. Normochromic - hemoglobin content is normal
2
Q
Macrocytic-Normochromic Anemias is a results of?
A
ineffective erythrocyte DNA synthesis,
3
Q
Give causes examples of Macrocytic-Normochromic Anemias
A
commonly caused by deficiencies of vitamin B12 (cobalamin) or folate (folic acid).
4
Q
Explain what happens with
A
Macrocytic-Normochromic Anemias
5
Q
A
-defective erythrocytes die prematurely, which decreases their numbers in the circulation, causing anemia.
6
Q
Eryptosis
A
Premature death of damaged erythrocytes,
7
Q
This is a common mechanism of cellular loss in individuals with anemia secondary to deficiencies of iron, infections (e.g., malaria, mycoplasma), chronic diseases (e.g., diabetes, renal disease), genetic diseases (e.g., beta-thalassemia, glucose-6-phosphate dehydrogenase [G6PD] deficiency, sickle cell trait), and myelodysplastic syndrome.3
A
Eryptosis
8
Q
What causes red blood cell growth and development to continue at unequal rates.
A
- Defective DNA synthesis in megaloblastic anemias
-DNA synthesis and cell division are blocked or delayed.
9
Q
Asynchronous development leads to what?
A
-an overproduction of hemoglobin during prolonged cellular division.
-This process creates a larger-than-normal erythrocyte with a disproportionately small nucleus.
10
Q
Give examples of macrocytic anemia
A
-Pernicous Anemia
-Folate Deficiency anemias
NUR1142
flashcards
Decks in class (112)
# Cards
-
Module 1 - Cellular Biology249
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Module 1 - Altered Cellular and Tissue Biology187
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Module 2 - Macrocytic - Pernicious Anemia43
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Module 2 - Microcytic-Hypochromic Anemias - IDA23
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Module 2 - Structure and Function of the hematological systm289
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Module 2 - Anemia General31
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Module 2 - Macrocytic - Folate Deficiency Anemias16
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Module 2 - Microcytic-Hypochromic Anemias3
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Module 2 - Microcytic-Hypochromic Anemias - Sideroblastic Anemia25
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Module 2 Macrocytic-Normochromic Anemias10
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Module 2 - Normocytic-Normochromic Anemias2
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Module 3 - Chapter 10159
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Module 3 - Chapter 10 - Metastasis54
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Module 3 - Chapter 10 - Chemotherapy13
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Module 3 - Chapter 10 - Radiation8
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Module 3 - Chapter 10 - Surgery3
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Module 3 - Immunotherapy16
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Module 3 - Chapter 10 - Infection10
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Module 3 - Prevalence51
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Module 3 Screening Guidelines11
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Module 3 - Antinausea medication14
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Module 3 - Pain Management67
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Module 4 - Chapter 6 - Innate Immunity - First Line50
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Module 4 - Chapter 6 - Innate Immunity Second Line Inflammation210
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Module 4 - Chapter 6 - Acute and Chronic Inflammation49
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Module 4 - Chapter 6 - Wound Healing81
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Module 4 - Chapter 6 - Rheumatoid Arthritis115
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Module 4 - Antihistamines122
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Module 4 Dmards:68
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Module 4 - BDMARDS6
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Module 4 - TNF Inhibitors6
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Module 4 - glucocorticoids101
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Module 4 - NSAID + Acetaminophen76
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Module 9: 1.Patho: Define the factors influencing infection. COPY359
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Module 9 2.Patho: Describes the four main classes of infectious microorganism: Bacteria65
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Module 9 2.Patho: Describes the four main classes of infectious microorganism: Fungus35
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Module 9 2.Patho: Describes the four main classes of infectious microorganism: Parasites/Protozoans28
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Module 9 2.Patho: Describes the four main classes of infectious microorganism: Parasites/Protozoans: Viruses74
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Module 9 3.Patho: Describe the three mechanisms pathogens use to block the immune system. (hint Power-Kean: Table 8.3 is a nice review)7
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Module 9 4.Patho: Describe the Host Defense Against Pathogens (HINT: Table 6.1 in Power-Kean) and the manifestation of associated signs/symptoms of infection13
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Module 9 5.Patho: Describe the gram stain process and list common gram positive and negative bacteria6
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Module 9 614
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Module 9 96
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Module 9 12 part 127
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Module 9 12 Part 233
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Module 9 12 Part 329
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Module 9 12 Part 453
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Module 9 12 Part 564
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Module 9 12 Part 687
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Module 9 14 Penicillin Part 1126
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Module 9 14 Penicillin Part 2116
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Module 9 14 Cephalosporin86
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Module 9 14 Macrolides Lincosamides Clindamycin99
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Module 9 14 Aminoglycosides Tetracycline Nitrofurantoin Fosfomycin323
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Module 9 14 Fluoroquinolones87
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Module 9 14 Metronidazole17
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Module 9 14 Sulfonamide Antibiotics and Trimethoprim222
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Module 9 14 Antifungals352
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Module 9 14 Antivirals258
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Module 9 14 Urethritis Cervicitis32
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Module 9 Part 2 Patho Otitis externa necrotizing malignant11
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Module 9 Part 2 Patho Otitis media12
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Module 9 Part 2 Patho Epiglottitis8
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Module 9 Part 2 Patho Laryngotracheobronchitis Croup14
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Module 9 Part 2 Patho Mononucleosis55
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Module 9: 1.Patho: Define the factors influencing infection.198
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Module 9: 1.Patho: Define the factors influencing infection. COPY COPY198
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Module 9 Part 2 Acute Pyelonephritis26
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Module 9 Part 2 Chronic Pyelonephritis14
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Module 9 Part 2 Vaginitis17
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Module 9 Part 2 Pelvic Inflammatory Disease10
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Module 9 Part 2 Otitis Externa – Adult Necrotizing (Malignant) MUMS5
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Module 9 Part 2 Otitis Media – Adult Acute8
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Module 9 Part 2 Chronic Suppurative Adult and Children7
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Module 9 Part 2 Otitis Media – Children Acute7
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Module 9 Part 2 Otitis Externa – Otomycosis5
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Module 9 Part 2 Otitis Externa Swimmer’s Ear Adult and Children5
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Module 9 Part 2 Pharyngitis Adult12
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Module 9 Part 2 Pharyngitis Children6
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Module 9 Part 2 Epiglottitis Supraglottitis – Medical Emergency6
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Module 9 Part 2 Pertussis5
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Module 9 Part 2 Croup MUMS4
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Module 9 Part 2 Community-acquired MRSA– Normal Host6
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Module 9 Part 2 Acute Urinary Tract Infection UTI Clinical Decision Aid5
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Module 9 Part 2 Acute Urinary Tract Infection – Female Uncomplicated5
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Module 9 Part 2 Acute Urinary Tract Infection – Children9
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Module 9 Part 2 Acute Cystitis Pregnancy7
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Module 9 Part Urinary Tract Infections Nursing Home Long Term Care7
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Module 9 Part 2 Pyelonephritis5
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Module 9 Part 2 Recurrent Cystitis – Female7
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Module 9 Part 2 Complicated Urinary Tract Infection Adult5
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Module 9 Part 2 Asymptomatic Bacteriuria7
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Module 9 Part 2 Vaginitis Trichomoniasis10
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Module 9 Part Vulvovaginal Candidiasis7
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Module 9 Part 2 Vulvovaginitis5
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Module 9 Part 2 Herpes Simplex Virus – Adult Genital Herpes6
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Module 9 Part 2 Cellulitis – Severe6
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Module 9 Part 2 Cellulitis – Mild6
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Module 9 Part 2 Acute Bronchitis5
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Module 9 Part 2 Sinusitis – ChildrenAcute6
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Module 9 Part 2 Seasonal Influenza – Treatment for those at Risk5
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Module 9 Part 2 Sinusitis – Adult Acute8
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Module 9 Part 2 Antibiotics and Acute Otitis Media5
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Module 9 Part 2 Seasonal Influenza – Post-exposure Antiviral Prophylaxis5
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Module 9 Part 2 External Genital Warts – Adult8
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Module 9 Part 2 Acute Rhinitis and Influenza Prevention4
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Module 9 Part 2 Cellulitis – Special Considerations Facial10
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Module 9 Part 2 Cellulitis – Special Considerations Diabetic Foot16
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Module 9 Part 2 Pelvic Inflammatory Disease – Outpatient6
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Module 9 Part 2 Herpes Simplex Virus – Children Genital Herpes7
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Module 9 Part 2 MRSA6
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Module 9 Part 2 Bites25
