Module 9 Part 2 External Genital Warts – Adult

Question 1

What are the patient-administered treatment options for external genital warts (EGW) in adults?

Answer 1

Imiquimod 3.75% cream, Imiquimod 5% cream, Podofilox 0.5% solution, Sinecatechins 10% ointment

Question 2

How long should patients use Imiquimod 3.75% cream and Imiquimod 5% cream for treating EGW?

Answer 2

Imiquimod 3.75% cream is applied once daily for up to 8 weeks. Imiquimod 5% cream is applied three times per week for up to 16 weeks.

Question 3

What is the recommended application regimen for Podofilox (podophyllotoxin) 0.5% solution?

Answer 3

Apply BID in the morning and at bedtime for 3 days, followed by no therapy for 4 days, and repeat if necessary (up to 4 cycles).

Question 4

How should Sinecatechins 10% ointment be applied for EGW treatment?

Answer 4

Apply 0.5 cm of ointment to each wart three times a day (TID) for up to 16 weeks.

Question 5

What are the provider-administered treatment options for EGW?

Answer 5

Cryotherapy, Podophyllin resin 10-25%, Trichloroacetic acid (TCA) 80-90%, laser therapy, and surgical removal methods.

Question 6

Why should genital warts be removed during pregnancy, and which treatments should be avoided during pregnancy?

Answer 6

Genital warts can proliferate and become friable during pregnancy. Podophyllotoxin and podophyllin should not be used. Cryotherapy, excision, and ablative methods are safer options.

Question 7

What considerations are important for patient-applied therapies for EGW?

Answer 7

Patients must be able to recognize and reach their warts and follow application instructions. Treatment for lesions > 4 cm2 may require medical supervision.

Question 8

How does cryotherapy work in treating EGW, and when should it be applied?

Answer 8

Cryotherapy is applied until a frozen area slightly larger than the wart is formed and can be repeated every 1-2 weeks for a maximum of 8 weeks.