Most Common Part 1 Flashcards

Compiled most commons

1
Q

Most common cause of congenital UTO

A

UPJ obstruction

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2
Q

Most common nonobstructive cause of
dilatation of the urinary tract observed in
prenatal utz

A

VUR

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3
Q

Most common vascular lesion in LN:

A

simple
vascular immune deposition

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4
Q

Most common lesion in SLE active class 3 and 4

A

simple
vascular immune deposition

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5
Q

Most common class LN where you find
Noninflammatory necrotizing vasculopathy
in arterioles

A

active class IV LN

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6
Q

Most common class of LN where
tubulointerstitial immune deposits are found

A

active proliferative class III and IV LN.

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7
Q

Most common pattern of glomerular
involvement for MCTD

A

membranous
nephropathy

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8
Q

Most common form of crescentic GN

A

Pauciimmune
rapidly progressive GN

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9
Q

Most common ANCA for px with WG w
granulomatous lesions

A

C ANCA against
PR3

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10
Q

The most common associated illness found
in patients with classic PAN

A

hepatitis B
infection

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11
Q

Most common organ affected in PAN

A

kidney

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12
Q

Most common clinical findings of true PAN

A

constitutional symptoms of fever, weight
loss, and malaise

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13
Q

For Microscopic polyangitis: most typical
histologic finding

A

focal segmental
necrotizing GN with crescents affecting from
few to many glomeruli

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14
Q

Most common ANCA in Churg Strauss
Syndrome

A

Most are P-ANCA and anti-MPO positive

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15
Q

Most common Ig deposited (seen in IF) in
HSP

A

IgA

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16
Q

Most common Ig depostited in LN

A

IgG

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17
Q

most common biopsy picture for
Goodpasture

A

diffuse crescentic GN
involving more than 50% of glomeruli, with
exuberant, predominantly circumferential
crescents

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18
Q

Most common IF finding Goodpasture

A

intense and diffuse linear staining for IgG
involving the GBM

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19
Q

Most common renal pathology in Sjogrens

A

tubulointerstitial nephritis

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20
Q

Most common renal findings in Sarcoidosis

A

granulomatous interstitial nephritis,
nephrolithiasis, and tubular functional
abnormalities

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21
Q

The most common organ involved in AL
amyloid

A

Kidneys, heart, peripheral nerves

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22
Q

Most common cause of death in amyloidosis

A

Cardiac involvement with associated heart
failure and arrhythmias

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23
Q

Most common renal presentation of
cryoglobulinemia

A

acute nephritic picture

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24
Q

Most common disease associated with
Mixed Cryo type II and III

A

HCV

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25
Q

Most pathognomonic ophthalmic abnormality
in Alport’s

A

Anterior lenticonus

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26
Q

Most common GN assocd with NSAIDS

A

MCD (with interstitial nephritis)

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27
Q

Most common GN assocd with Heroin

A

FSGS

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28
Q

Most common GN assocd with Gold/Pencillamine/carcinoma/Hep B

A

Membranous

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29
Q

Most common risk factor for HIVAN

A

IV drug use

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30
Q

Most common glomerular lesions among
whites who have HIV (no IV drug use)

A

diffuse mesangial hyperplasia

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31
Q

Most common pattern of IMMUNE
COMPLEX mediated GN seen in HIV

A

MGPN

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32
Q

Most typical GN lesion in IE:

A

focal and
segmental endocapillary proliferative GN w
focal crescents

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33
Q

The most common pattern of Monoclonal Ig
Deposition disease

A

LCDD – light chain
depos. Dse

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34
Q

Major lesion of DMN Type 1 leading to renal dsynfxn:

A

Mesangial expansion

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35
Q

Major cause of mortality among T1DM

A

ESRD

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36
Q

Major cause of fistula malfunctions in DM px

A

inadequate arterial inflow

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37
Q

Major nutritional problem of PD

A

gain of glucose

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38
Q

Most important host defense that maintains
sterility of urine

A

normal, unobstructed
voiding

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39
Q

Most abundant protein in urine

A

Tamm
Horsfall protein

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40
Q

Most common cytokines involved in UTI

A

IL-6
and IL-8

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41
Q

Most UTIs post KT occur

A

first 3 months

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42
Q

Most common pathogen UTI post KT

A

Enterobac – E. coli

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43
Q

Most common pathogen Emphysematous
cystitis/PN

A

E. coli, Kpn

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44
Q

Most common pathogen Xanthogran PN

A

P. mirabilis (followdb by Ecoli)

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45
Q

Most common urine picture in GUTB

A

sterile pyuria with hematuria

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46
Q

Most common CT finding for GUTB

A

renal calcification

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47
Q

Most common pathogen cystitis

A

E. coli
(2nD:S. saprophyticus)

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48
Q

Strongest assocn of recurrent acute cystitis
in postmenop women

A

History of prior UTI at
a younger age

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49
Q

The most common pathogen causing
asymptomatic bacteriuria in men >65

A

CONS

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50
Q

Most common and important parastitic
infestation of Urinary tract

A

Schistosoma
hematobium

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51
Q

Most common extrarenal findings in
Atheroemboilic dse

A

Cutaneous symptom

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52
Q

Most common internal organ affected by
Atheroembolic dse

A

kidney

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53
Q

Most common intervention reported to incite
chole embolizaion

A

arteriographic procedures
(coro angio)

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54
Q

Most common sickle cell variant to manifest
with gross hematuria

A

Hb-AS2

55
Q

Most common sickle cell variant to manifest
with proteinuria

A

homozygous Hb-SS

56
Q

Most common source of bleeding in papillary
necrosis in px with SC:

A

Left kidney

57
Q

Most prominent lesions seenin pathology of
px with sickle cell disease:

A

medullary lesions

58
Q

Most common cause of renal failure in sickle
cell diseae

A

FSGS

59
Q

Most common location of Renal artery
aneurysm

A

bifurcation of renal artery or in first order branch arteries
saccular type

tto in situ aneurysmectomy
and revasularization

60
Q

Most common manifestation of chronic
dissection of renal artery aneurysm

A

Renovascualar HPN

61
Q

RVT in adults most commonly assocated
with

A

Nephrotic syndrome

62
Q

Most common precipitating event for type 1
HRS:

A

SBP

63
Q

Principal risk factor for devt of AKI

A

CKD

64
Q

Most common immunologic cause of
Intersitial nephritis

A

Acute allograft rejection
in transplant px

65
Q

Second most common cause of intrinsic AKI

A

nephrotoxic

66
Q

Most nephrotoxic antibiotic

A

Neomycin

67
Q

Most common site of cisplatin nephrotoxicity
in rats

A

S3 segment of PT in corticomedullary
region

68
Q

Most common cause of postrenal azotemia

A

bladder neck obstruction

69
Q

Most common segment in PT damaged in
ischemic injury

A

S3

70
Q

Mot common segment involved in toxic
nephropathy

A

S1, S2

71
Q

Most common intrinsic AKI that presents with
FeNa of <1%:

A

radiocontrast, rhabdo

72
Q

Most common location of extra adrenal
tumor in pheo

A

Abdomen - superior and
inferior paraaortic areas

73
Q

Most common / α-blocker of choice for med
tx of pheo

A

phenoxybenzamine

74
Q

The most common routine laboratory finding
in GRA

A

low PRA level

75
Q

Highest level of NOS activity

A

medullary collecting ducts

76
Q

FiBromuscular dysplasia (cause of RAS)
assocd s string of beads appearance

A

Medial fibroplasia

77
Q

Renal reperfusion injury most pronounced in

A

prox tubules

78
Q

FMD more common in right renal artery

A

women

79
Q

Most common renovascular lesion

A

Atherosclerosis affecting renal arteries.
(ARAS)

80
Q

Most cmon presentation RAS

A

worsening of preexisting hpn

81
Q

Most common cause of DGF in deceased
donor kidney recipients

A

ischemic ATN

82
Q

Most common cause of allograft loss in the
first week

A

Acute vascular thrombosis

83
Q

Most common time period acute rejections
occur in:

A

first 6 mths

84
Q

Most common time period acute rejections

A

first 6 mths

85
Q

Most commonly implicated cause of AIN in
KT px:

A

TMP SMX

86
Q

Best test to demonstrate bladder leak:

A

cystography

87
Q

Most commn time frame that UTO occurs
post KT

A

early post KT period (within 6 mos)

88
Q

most important cause of allograft dysfunction
after the first 6 to 12 months

A

Chronic
allograft injury (CAI).

89
Q

Principal risk factors in persistent hyperpara
in post KT:

A

degree of pre transplant
hyperpara, duration of dialysis

90
Q

Principal cause of hyperK in post KT

A

CNI

91
Q

The most important cause of hyperuricemia
and gout after transplant

A

CNIs (particularly
CYA)

92
Q

Most commonly affected bone in
Osteonecrosis post KT

A

the femoral head

93
Q

Most sensitive diagnostic modality to dx
osteonecrosis

A

MRI

94
Q

Most of the bone loss in post KT
osteoporosis occurs in the

A

first 6 months
after transplant.

95
Q

Most common cause of early and late
allograft loss

A

Death with a functioning
allograft (mc. Casue: cardiovascular disease)

96
Q

Most common type of PTLD post transplant

A

non-Hodgkin’s lymphomas

97
Q

Most common time frame PTLD occurs post
KT:

A

24 months after transplant

98
Q

Major risk factor for pre
eclampsia

A

APAS (followed by Renal
disease)

99
Q

Most reliable sign of superimposed pre
eclampsia on chronic HPN (in the absence of
underlying renal disease

A

new onset
proteinuria (>300 mg/day) usually with
worsening HPN

100
Q

The most common cause of AKI during
pregnancy

A

prerenal azotemia due to
hyperemesis gravidarum or vomiting from
acute pyelonephritis

101
Q

Most common stones in pregnancy

A

Calcium
oxalate and calcium phosphate

102
Q

Most common renal problem encountered
during gestation

A

infection of urinary trac

103
Q

Most common complication of pregnancy in
KTR:

A

hypertension

104
Q

Most relevant phosphatonin in the setting of
CKD

A

FGF23

105
Q

Most important transport channel in the
transcellular uptake of Ca in the kidneys

A

TRPV5 (as opposed to intestines: TRPV 6)

106
Q

highest density of protein expression of CasR

A

cortical thick ascending
limb.

107
Q

most important determinantin minute to
minute PTH secretio

A

extracellular
concentration of ionized calcium

108
Q

Most potent phosphate-binding compounds

A

Aluminum

109
Q

most effective agent available for reducing
serum PTH levels in patients with ESRD

A

Cinacalcet

110
Q

The most frequent side effect of cinacalcet

A

nausea and vomiting

111
Q

Most common and most troublesome side
effect of icodectrin

A

Skin rashes

112
Q

most common pathway of invasion in
peritonitis

A

catheter’s lumen
(the next most frequent pathway is by the
periluminal route)

113
Q

Most common organism causing peritonitis

A

G (+) particularly S. epidermidis

114
Q

Most common overt complication of primary
Hyperpara

A

nephrolithiasis

115
Q

Most important inhibitor of stone formation

A

citrate

116
Q

Most important regulator of citrate reabsorption

A

cell pH in the proximal tubule

117
Q

The most prevalent cause of hyperuricosuria
in px with kidney stones

A

excessive dietary
purine

118
Q

Most important and invariant finding in uric
acid nephrolithiasis

A

low urinary pH

119
Q

Most common encountered stone with
HYPERURICOSURIA

A

ca oxalate

120
Q

Most important stimuli for AVP secretion
under physiologic conditions

A

osmotic
pressure of plasma

121
Q

Most common mutation in Congential NDI

A

mutations of the AVP V2 receptor

122
Q

most common cause of drug induced NDI

A

lithium

123
Q

Most common causes of
pseudohyponatremia

A

primary or secondary
hyperlipidemic disorders.

124
Q

Most common extrarenal cause of
hypovolemic hyponatremia:

A

gastrointestinal
disease with vomiting or diarrhea.

125
Q

Most common cause of diuretic induced
hyponatremia

A

thiazides

126
Q

Most common cause of hyponatremia in
hospitalized px:

A

SIADH

127
Q

Most common tumor causing SIADH

A

Small cell Ca

128
Q

Most common side effect of Conivaptan

A

injection site reactions

129
Q

Most commonly expressed KCC in the proximal tubule

A

KCC3 , KCC4

130
Q

Most AQP1 in the tDL is expressed in what
type of epithelial cell:

A

type II

131
Q

Most AQP1 expressed in this segment

A

thin descending limb of LOH (OM)

132
Q

NKCC2 protein with the highest affinity for
Cl

A

NKCC2B

133
Q

Most NaKATPase expressed in

A

DCT