Flashcards in MS Deck (20):
MS affects what part of the brain?
white matter and spinal cord
near ventricles and optic nerve
cerebellum, brain stem, basal ganglia
*depending on what part of brain affects = sx
MS - cx?
suspicions of genetics
MS - imaging?
plaques (near ventricle and optic nerve)
MS - population?
MS - sx?
bowel, bladder, sexual fxn changes
worsening sx after exposure of some out of norm temp (bath tub)
tingling down back into limbs when flexing neck
MS - classification?
never return to baseline
worse sx w/ every episode
starts off as relapsing but turns into primary progressive (never getting better/not episodic)
not episodic - always getting worse
episodic and progressively getting worse
What is not typical of MS?
cortical deficits (alexia, agraphia, apraxia, aphasia)
rigidity (basal ganglia)
MS - dx?
CIS - lasts 24 hrs d/t inflammation/demylination
nothing definitive - clinical dx (but early dx = slows progression)
MS - PE/exams?
25 foot timed walk
9 hole peg (UMN)
MS - imaging?
MRI (even for baseline)
b/c if plaques are found 1st around - does not tell us when plaques were there - but if f/u is done then there is a timeline (plaques along ventricles over short pd of time = most likely MS though NOT diagnostic)
MS - CSF?
not needed unless MRI is not good enough
+protein, norm glucose
CSF oligoclonal banding
CSF IgG synthesis
MS - tx?
nothing - DMT (Dz modifying therapy)
-does not reverse sx, resuce acute MS relapses, slow dz
acute? - HD, short corticosteroids; plasma exchange
Beta interferons (pallative)
Vita D (doesn't hurt to give em; may reduce relapse if it works)
OT/PT (to make them more functional)