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Musculoskeletal System > Muscle Physiology > Flashcards

Flashcards in Muscle Physiology Deck (3)
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Gatekeeper system?

[ca2+] increases
Ca2+ binds to troponin
Tropomyosin moves out the way
Actin exposed for myosin
[ca2+] decreases
Ca2+ dissociates from troponin
Tropomyosin attached to actin


Rope system?

ATP binds to myosin
Myosin detaches from actin
ATP -> ADP + Pi
Myosin cocked into high energy conformation
Pi released
Myosin binds to and pulls actin
ADP released


What is myosin?

An ATPase enzyme and superclass of motor proteins