muscular system Flashcards

1
Q

myofibrils

A

contain microfilaments divided into sarcomeres

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2
Q

sarcomeres

A

individual contractile units separated by a border (Z-line)

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3
Q

sarcoplasmic reticulum

A

stores calcium and surrounds myofibrils

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4
Q

sarcoplasm

A

same thing as cytoplasm

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5
Q

sarcolemma

A

plasma membrane of muscle cells that can propogate action potentials that are invaginated by T-tubules (channels for ion flow)

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6
Q

mitochondria

A

present in large amounts in myofibrils

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7
Q

as submaximal stimulus increases

A

motor unit recruitment increases

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8
Q

when a maximum stimulus is reached

A

all motor units are recruited

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9
Q

cardiac muscle

A
  • striated muscle
  • one or two central nuclei
  • cells separated by intercalated discs that have gap junctions
  • lots of mitochondria
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10
Q

smooth muscle

A
  • lacks striation
  • one central nucleus
  • stimulated by autonomic nervous system
  • does not utilize sarcomeres
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11
Q

skeletal muscle

A
  • striated
  • multiple nuclei
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12
Q

neuromuscular pathway

A
  1. action potential of a neuron releases ACh at a neuromuscular junction
  2. an action potential is generated on the sarcolemma and throughout T-tubules
  3. sarcoplasmic reticulum releases calcium
  4. calcium binds to troponin on the actin helix, allowing myosin to bind
  5. myosin cross-bridges form and contraction occurs
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13
Q

sliding filament model (contraction)

A
  1. calcium exposes binding sites on actin
  2. myosin head attached to actin filament cross-bridge
  3. inorganic phosphate is released from the myosin head initiates power stroke
  4. new ATP attaches to myosin head –> cross bridges unbind myosin and actin unbind
  5. when ATP is converted to ADP+Pi, the myosin head is cocked back
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14
Q

what happens if no ATP is available

A

the muscle is stuck in contraction (rigor mortis)

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15
Q

think filaments

A

actin

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16
Q

thick filaments

A

myosin