Musculoskeletal prac Flashcards
(18 cards)
In the formation of bone, osteoblasts secrete _____
Osteoid
What’s the intermediary tissue involved in the healing of fractures that forms in & around the fracture site?
Callus
What is produces by the chondrocytes in articular cartilage is the process of OA?
Inflammatory cytokines
What is believed to play a role in reduced bone density in older people?
Excessive osteoclast activity
What are the two cell types of the synovium?
Type A cells
Type B cells
What are the Type A cells of the synovium?
Macrophage-like synoviocytes
What are the Type B cells of the synovium?
Fibroblast-like synoviocytes
T/F the synovium has a blood supply
True! a rich one
What forms the synovial fluid?
Plasma filtrate from the synovial capillaries + lubricating substances like hyaluronic acid
What is hyaline cartilage made of?
Chondrocytes + ECM
T/F hyaline cartilage has a blood supply
False
What is the ECM of hyaline cartilage made of?
Type II collagen Hyaluronic acid Proteoglycans GAGs Water
What proportion of hyaline cartilage is water & why?
70% by weight, as the structures are very hydrophilic
What’s an example of a proteoglycan?
Aggrecan
What’s an example of a GAG?
Chondroitin sulphate
What runs within a haversian canal?
Blood vessels & nerves
Supportive CT
What are the structures that radiate from osteocytes within their lacunae to other osteocytes? What’s their purpose?
Canaliculi allow circulation of ECF and metabolites between the osteocytes
What are the two main types of ossification?
Endochondrial
Intramembranous
