Mutations Flashcards

1
Q

Point

A
Single base pair changed
insertion / addition
Deletion
Substitution 
Most common
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2
Q

Bigger

A

Translocation
Deletion
More than single base pair
Inversion

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3
Q

Mutations

A

DNA had changed

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4
Q

Wild type

A

No mutated

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5
Q

Mutations three categories

A

Chemical energy
high energy radiation
Some viruses

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6
Q

Examples of high energy radiation

A

X rays

Ultra violent sunlight

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7
Q

Examples of viruses

A

HIV

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8
Q

HIV

A

Cause surgical cancer

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9
Q

Example of chemical

A

Gasoline, darkened meat, hot dog (nitrates turned to nitrosmein, hair dye

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10
Q

Carcinogen

A

Cause cancer

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11
Q

Carcenoman

A

Type of cancer

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12
Q

Inversion

A

Piece of DNA out own DNA and reinsert upside down or opposite directions

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13
Q

Deletion

A

Piece of DNA break off, is lost

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14
Q

Examples of deletion (bigger)

A

5 million base pair lost, autism

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15
Q

Effects of deletion and addition

A

Cause frame to shift = different amino acid sequence

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16
Q

Insertion / addition

A

Single base pair stuck, and doesn’t belong there

17
Q

Amino acid sequence

A

Determine secondary and tertiary structure

18
Q

Substituon

A

Have one base pair structure for another l

Cause amino acid to be different

19
Q

Examples of subsituoon

A

Sickle cell FFI

20
Q

FFI

A

Fatal familia insomnia

Will die when sleep

21
Q

Hemoglobin

A

In red blood cell
Transport oxygen
300 million in red blood cells
207 amino acids long

22
Q

Sickle cell

A

Cause red blood cells to be sickle shaped

23
Q

Translocation

A

Piece of DNA coming out of own DNA molecule and insert to different chromosome

24
Q

Why remove non coding

A

before leave nucleus have to remove non coding region of mRNA

25
Coding
Codes for specific amino acid sequence
26
Non coding
Not coding for amino acid sequence
27
Splice some
Cut out introns | Reattach exons
28
Result
Functional rna
29
DNA printing
Use non coding DNA to determine junk DNA, use for determining ID
30
What is splice some made out of
Protein, sRNA and other proteins
31
Frame shift mutations
Insertions and deletions