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Flashcards in Mycobacterium - Exam 2 Deck (31):
1

What is the best way to stain Mycobacterium and why?

Acid-fast stain

LIPID RICH CELL MEMBRANE!

Long and complex micolic acids present in cell membrane

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2

True/False. Mycobacterium in anaerobic.

FALSE! 

AEROBIC!

3

What are the important diseases caused by Mycobacterium spp.?

Tuberculosis

Paratuberculosis (Johne's Disease)

Granulomatous disease

4

What is the most important virulence factor that Dr. Soto does not want us to forget about Mycobacterium?

LIPID RICH CELL WALL!!

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5

True/False. Tuberculosis is not a reportable disease.

FALSE! REPORT IT!

6

How is Mycobacterium transmitted?

Via the respiratory and alimentary routes

MILK FROM INFECTED MAMMARY GLANDS IS A SUPER IMPORTANT WAY PEOPLE GET THIS!

7

Which species of Mycobacterium affects the respiratory tract, adjacent lymph nodes, and serous cavities?

Mycobacterium bovis

8

What species of Mycobacterium mainly infects swine and how?

M. Bovis via the alimentary route

9

Which species of Mycobacterium mainly infects cats and dogs? 

M. Bovis

10

Primates are susceptible to which species of Mycobacterium?

M. bovis (via ingestion [unpastuerized milk])

M. tuberculosis (aiborne route)

11

Birds are naturally susceptible primarily to which species of Mycobacterium?

M. avium

12

True/False. There is no zoonosis with tuberculosis.

False! REVERSE ZOONOSES!

13

True/False. Tuberculosis is typically a disease of captivity and domestication.

True

14

Which of the following is NOT a characteristic of tubercle bacilli:

-very hardy

-resistant to many antimicrobial and disinfectants

-survive short periods in soil and resist drying

-survive short periods in soil and resist drying

THIS IS NOT A CHARACTERISTIC OF TUBERCLE BACILLI

they survive for LONG periods in soil and resist drying

15

Which species of Mycobacterium causes Johne's disease in cattle?

M. avium subsp. paratuberculosis

16

True/False. Johne's disease is a reportable disease.

True! REPORT IT!

17

What is the main reservoir for M. avium subsp. paratuberculosis?

Sympomatic and asymptomatic wild and domestic ruminants, swine and rabbits

18

What is the main mode of transmission for M. avium subsp. paratuberculosis?

Fecal-oral 

(in utero infection and ingestion of contaminated colostrum or milk are also possible routes)

19

Which animals are the most susceptible to M. avium subsp. paratuberculosis? Young or old animals?

Young animals

20

What type of stain is used for acid-fast stain?

Ziehl-Neelsen 

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21

True/False. M. avium subsp. paratuberculosis has a laboratory growth dependency for mycobactin.

True 

22

The failure to eliminate the bacteria from host is due to the activation of what being compromised?

IFN-gamma

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23

Which cattle breeds are predisposed to Johne's disease?

Guernsey and Jersey

24

Which species of Mycobacterium causes feline leprosy?

M. lepraemurium

(chronic noduloulcerative-nontuberculous mycobacterial infection of the skin)

25

What causes canine leproid granuloma syndrome?

An uncultured, saprophytic species of Mycobacterium

26

What causes ulcerative dermatitis of dogs and cats?

rapidly growing Mycobacteria 

M. fortuitum, M. chelonae

27

What is bovine facry and what causes it?

Bovine myobacterial ulcerative lymphangitis

Caused by: M. farcinogenes and/or M. senegalenses

(nodulo-ulcerative skin lesion in cattle on the lower extremities and ventral trunk)

28

Which species of Mycobacterium affects marine and freshwater organsims?

M. marinum

29

Which species of Mycobacterium is present in tropical and temperate climates?

M. fortuitum

30

Which species of Mycobacterium affects cold water salmonids?

M. chelonae

31

Which of the following grows the fastest in the laboratory? M. fortuitum, M. chelonae, or M. marinum?

M. fortuitum and M. chelonae are grow fastor than M. marinum which is a great diagnositic tool.