MYCOVIRO - CH 60 PPT part 2 Flashcards Preview

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Flashcards in MYCOVIRO - CH 60 PPT part 2 Deck (35):
1

Endemic Mycoses
North American Blastomycosis


Blastomyces dermatitidis

2

Endemic Mycoses
Broad based yeast

Blastomyces dermatitidis

3

Endemic Mycoses
Dumb-bell conidia, lollipop conidiophores

Blastomyces dermatitidis

4

Endemic Mycoses
Cave disease, spelunker’s disease

Histoplasma capsulatum

5

Endemic Mycoses
Soil rich in bird or bat guano

Histoplasma capsulatum

6

Endemic Mycoses
Small yeast found inside macrophages


Histoplasma capsulatum

7

Endemic Mycoses
Echinulate macroconidia

Histoplasma capsulatum

8

Endemic Mycoses
Dimorphism is important in confirming ID

Histoplasma capsulatum

9

Endemic Mycoses
San Juaquin Valley Fever

Coccidioides immitis

10

Endemic Mycoses
Dissemination in Filipinos and African Americans

Coccidioides immitis

11

Endemic Mycoses
Direct exam reveal spherules (sputum, lung aspirate)

Coccidioides immitis

12

Endemic Mycoses
Produce arthroconidia separated by disjunctor cells

Coccidioides immitis

13

Endemic Mycoses
South American Blastocycosis

Paracoccidioides brasiliensis

14

Endemic Mycoses
Budding yeasts with multiple buds (mariner’s wheel, mickey mouse cap)

Paracoccidioides brasiliensis

15

Opportunistic Mycoses
- produce pseudohyphae (true hypahe?)









Candida albicans

16

Opportunistic Mycoses
- germ-tube(+)

Candida albicans

17

Opportunistic Mycoses
- carbohydrate assimilation tests to identify other species

Candida albicans

18

Opportunistic Mycoses
- chlamydospores in cornmeal agar

Candida albicans

19

Opportunistic Mycoses
- urease(-)

Candida albicans

20

Opportunistic Mycoses
Monomorphic



Aspergillus spp

21

Opportunistic Mycoses
Found in soil
May produce aflatoxin (hepatotoxin)

Aspergillus spp

22

Opportunistic Mycoses
Identified by the morphology or conidial heads

Aspergillus spp

23

Opportunistic Mycoses
Found in soil especially those with pigeon droppings


Cryptococcus neoformans

24

Opportunistic Mycoses
Urease (+)

Cryptococcus neoformans

25

Opportunistic Mycoses
Mucoid colonies

Cryptococcus neoformans

26

Opportunistic Mycoses
Cryptococcal antigen test (latex agglutination)

Cryptococcus neoformans

27

Opportunistic Mycoses
Encapsulated yeast in India ink preparation

Cryptococcus neoformans

28

Opportunistic Mycoses
Dimorphic

Penicillium marneffei

29

Opportunistic Mycoses
Cutaneous and mucocutaneous infection

Penicillium marneffei

30

Opportunistic Mycoses
Mycelial forms produce brush-like conidiophores (penicillus)

Penicillium marneffei

31

Opportunistic Mycoses
Direct exam reveals annelid formation

Penicillium marneffei

32

Opportunistic Mycoses
Interssticial cell pneumonia in immunocompromised
Previously classified as protozoan

Pneumocystis jiroveci

33

Opportunistic Mycoses
2 forms of Pneumocystis jiroveci

troph and cyst

34

2 forms of Pneumocystis jiroveci
more common but difficult to identify

trophozoite

35

2 forms of Pneumocystis jiroveci
ping-pong balls

cysts

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