nbme 19 Flashcards
what type of HIV med causes lipodystrophy
proteases
(teases you into thinking you are losing weight, but it is really just gathering in your gut)
pt has heparin during preg and her platelet count drops significantly, why?
ITP
antibodies to platelets
Rifampin inhibits
RNA synthesis (via inhibiting DNA dependent RNA synthesis)
meningioma
occur near the surface of the brain
is extra-axial (external to brain parenchyma)
nerve that detects stretch in bladder
detrussor contraction nerve
internal sphincter relaxation
pelvic
hypogastric
pudendal
no tonsils
BRUTON!
bruTON
up to 3 days wound healing
inflammatory
platelets, neutrophils, macrophages
clot formation, increased vessel perm, neutrophil migration
(at day 2 macrophages are clearing the debris)
wound healing 3 days-weeks
proliferative phase
fibroblasts involved, myofibroblasts, endothelial keratinocytes and macrophages
Depositon of granulation tissue and TYPE 3 COLLAGEN, also angiogenesis, disollution of clot, wound contraction (from myofibroblasts)
weeks –> months wound healing
Remodeling phase
fibroblasts ONLY
replace Type 3 collagen –> Type 1 Collagen (to increase tensile strength)
metalloproteases do tissue remodeling
what is overexpressed in keloid scar
PDGF
excess collagen depositon by fibroblasts
erythyma marginatum
erythema migrans
erythema multiforme
marginatum –> JONES criteria
migrans –> lymes
multiforme –> macules, vacules (nonspecific for multiform rash) can be seen in HSV, mycoplasma)
conversion disorder
loss of sensory or motor function (paralysis, blindness, muteness) following an acute stressor
pt is indifferent to sx
Think teenage girl!
temperature to kill prion
kill spore
NO temp, not living
121 for 15 min in autoclave (need STEAM, not just high temp)
sterile urine cultures with pyuria
chlamydia or neisseria
pyuria =pus