Neoplasia- staining

Question 1

what type of immunohistochemical stain would you use for the following tissue type?

Epithelium

Answer 1

Keratin

Question 2

what type of immunohistochemical stain would you use for the following tissue type?

Mesenchyme

Answer 2

Vimentin

Question 3

what type of immunohistochemical stain would you use for the following tissue type?

Muscle

Answer 3

Desmin

Question 4

what type of immunohistochemical stain would you use for the following tissue type?

Neuroglia

Answer 4

GEAP

Question 5

what type of immunohistochemical stain would you use for the following tissue type?

Neurons

Answer 5

Neurofilament

Question 6

name the 5 immunohistochemical stain used for intermediate filments

Answer 6

• Keratin (epithelium)
• Vimentin (mesenchyme)
• Desmin (muscle)
• GEAP (neuroglia)
• Neurofilament (neurons)

Question 7

what type of immunohistochemical stain would you use for the following tissue type?

Prostatic epithelium

Answer 7

PSA

Question 8

what type of immunohistochemical stain would you use for the following tissue type?

Breast epithelium

Answer 8

ER

(estrogen receptor)

Question 9

what type of immunohistochemical stain would you use for the following tissue type?

Thyroid follicular cells

Answer 9

Thyroglobulin

Question 10

what type of immunohistochemical stain would you use for the following tissue type?

Neuroendocrine cells

(small cell carcinoma of lung and carcinoid tumors)

Answer 10

Chromogranin

Question 11

what type of immunohistochemical stain would you use for the following tissue type?

Melanoma

Answer 11

S-100