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Flashcards in Nephritic/nephrotic syndrome Deck (18):
1

3 most important nephritis for test are post infectious, lupus and granulomatosis with polyangiitis

ok

2

Antibiotics do not help post infectious glomerulonephritis and most common in kids (makes sense b/c kids get strep)

Tests for it?
Finding on hits?

Tx?

Antistrep O if previous strept throat, but if previous skin impetigo, DNAse B will be there (for strep throat and Strep B)

Histo is subepithelial humps are bumpy ALSO MESANGIAL is crazy cellular (can't see capillaries)

Self limiting treatment

3

General treatment for nephritic syndrome?

steroids, acei's and statins over and over

4

Most common nephrotic in children?

Tx?

Minimal change edema

pretty normal biopsy

Steroids

5

Membranous nephropahty on biopsy?

Spike and Dome and thickening of membrane (MEMBRANE makes sense)

Domes!! spikes of super thick membrane bumping up

6

Hep b associated with what nephropathy?

Membranous nephropathy (used to be most common)

7

Tram track appearance is in what nephrotic syndrome? What causes the syndrome?

Membranoproliferative glomerulonephritis

Infection or autoimmune disease and is TRAM TRACK appearance as membrane thickens

Lupus can cause it
Hep B and C (more common with C)

Think B is before C and membranous is shorter than menmbranoprolipherative

8

Diabetes affect on kidney?

Diabetic nephropathy with KIMMELSTEIN wilson nodule

Round pink nodule. Dense mesangium without many cells

9

What causes hyaline casts?

Nonpathologic. Comes with dehydration

10

Red cell casts?

Glom bleeding

11

White cell asts?

Pyelo or tubular interstitial disease or glomerular disorder

12

What causes epithelial casts?

Acute glom nephritis causign desquamation of glomeruli

13

What causes granular casts?

ATN!!! breakdown of other casts usually. They are brown

14

Casts are nonspecific, but might push in a certain direction if question stem/history are helpful

oh ok

15

FENa for prerenal?

less than 1%

Intrinsic or post renal is more than 2%

16

Calculation of FENa?

(Urin Na/Serum Na)/(Urin cr/serum Cr)

17

Chronic kidney disease meds?

Why beta blockers!

BP CONTROL and LIPID with statins and ANEMIA iron and expo Vit D, Phos-Lo, Aspirin!!!!

Diuretics to get edema out
ACEi or ARB unless high potassium!
Beta blockers to reduce CAD risk!!!
CCB, be careful for edema

18

Dialysis mnemonic?

AEIOU

Acidosis
Electrolytes (POTASSIUM)
Ingestion of toxin
Overload of fluid
Uremia