Flashcards in Nephritic/nephrotic syndrome Deck (18):
3 most important nephritis for test are post infectious, lupus and granulomatosis with polyangiitis
Antibiotics do not help post infectious glomerulonephritis and most common in kids (makes sense b/c kids get strep)
Tests for it?
Finding on hits?
Antistrep O if previous strept throat, but if previous skin impetigo, DNAse B will be there (for strep throat and Strep B)
Histo is subepithelial humps are bumpy ALSO MESANGIAL is crazy cellular (can't see capillaries)
Self limiting treatment
General treatment for nephritic syndrome?
steroids, acei's and statins over and over
Most common nephrotic in children?
Minimal change edema
pretty normal biopsy
Membranous nephropahty on biopsy?
Spike and Dome and thickening of membrane (MEMBRANE makes sense)
Domes!! spikes of super thick membrane bumping up
Hep b associated with what nephropathy?
Membranous nephropathy (used to be most common)
Tram track appearance is in what nephrotic syndrome? What causes the syndrome?
Infection or autoimmune disease and is TRAM TRACK appearance as membrane thickens
Lupus can cause it
Hep B and C (more common with C)
Think B is before C and membranous is shorter than menmbranoprolipherative
Diabetes affect on kidney?
Diabetic nephropathy with KIMMELSTEIN wilson nodule
Round pink nodule. Dense mesangium without many cells
What causes hyaline casts?
Nonpathologic. Comes with dehydration
Red cell casts?
White cell asts?
Pyelo or tubular interstitial disease or glomerular disorder
What causes epithelial casts?
Acute glom nephritis causign desquamation of glomeruli
What causes granular casts?
ATN!!! breakdown of other casts usually. They are brown
Casts are nonspecific, but might push in a certain direction if question stem/history are helpful
FENa for prerenal?
less than 1%
Intrinsic or post renal is more than 2%
Calculation of FENa?
(Urin Na/Serum Na)/(Urin cr/serum Cr)
Chronic kidney disease meds?
Why beta blockers!
BP CONTROL and LIPID with statins and ANEMIA iron and expo Vit D, Phos-Lo, Aspirin!!!!
Diuretics to get edema out
ACEi or ARB unless high potassium!
Beta blockers to reduce CAD risk!!!
CCB, be careful for edema