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Flashcards in Nephro-urolithiasis Deck (25):

Which gender is more commonly affected by stones?


M:F ratio of 3:1


Peak age in men is 30


Chance of stone recurrence is 50% within 10 years, 10% within a year


What are the types of stones and their incidence?

¨Calcium oxalate  45%

¨Calcium oxalate + phosphate  25%

¨‘Triple phosphate’ (infective)  20%

¨Calcium phosphate     3%

¨Uric acid     5%

¨Cystine     3%


What are the symptoms and signs?

Renal pain (fixed in loin)

Ureteric colic (radiating to groin)

Dysuria / haematuria /testicular or vulval pain

Urinary infection

Loin tenderness



What are initial investigations for kidney stones?

Blood tests - FBC, U&E, Creatinine

Calcium, Albumin, Urate


Urine analysis and culture

24hr urine collections


MIght show low citrate - citrate can help prevent crystal formation


What are the readiological investigations for stones?

KUB - kidney, ureter, bladder (shows up the calcium containing stones - over 90% of stones)


IVU - intravenous urogram



What are indications for surgial treatment?


Recurrent gross haematuria.

Recurrent pain and infection.

Progressive loss of kidney function.

Patient occupation.


What are the techniques for surgical treatment?

Open Surgery (now rare)

Endoscopic Surgery

ESWL - extra corporeal shockwave therapy


Renal stones

Ureteric stones

Bladder stones


What are the advantages and disadvantages of open stone surgery?

The advantage of open surgery is:

Single procedure with the least recurrence rate.

The disadvantages of open  surgery are:

 arge scar, long hospital stay, general wound complications, longer recovery.


What are indications for open surgical stone treatment?

Non-functioning infected kidney with large stones necessitating nehrectomy


Cases which for technical reasons cannot be managed by PCNL or ESWL.


PCNL - Percutaneous Nephrolithotomy 


When is there a need for simple partial and total nephrectomy?

Non functioning kidney with large staghorn stones or elderly frail patients with complex stones and normal contralateral kidney.


Note: ¨Contralateral stone formation in up to 30% after total nephrectomy has been reported.


What are indications for PCNL?

Large stone burden (risk of Steinstrasse)

Associated PUJ stenosis.

Infundibular stricture.

Calyceal diverticulum.

Morbid obesity or skeletal deformity.

ESWL resistant stones e.g. Cystine.

Lack of availability of ESWL.


What are contraindications for PCNL?

Uncorrected coagulopathy.

Active Urinary Tract Infection.

Obesity or unusual body habitus unsuitable for X-ray tables.

Relative contraindications include small kidneys and severe perirenal fibrosis.


What are the local complications of PCNL?

Pseudoaneurysm or AV fistula  0.5-1%

UT injury:   Pelvic tear  8-15%

  Ureteral tear  5%

  Stricture of PUJ  0.1-0.8%


What injury to adjacent organs can occur as a result of PCNL?

Adjacent organs:

Bowel injury 0.1%

Pneumothorax 0.1 - 0.3%

Liver, Spleen (very rare)


What are the systemic complications of PCNL?

Fever, sepsis - 0.2-0.6%

Myocardial infarction - 0.1-0.4%


Mechanism of ESWL


What is often the first line treatment for renal and ureteric calculi?



¨Treatments are usually done on a on a day-case basis with simple analgesia

Can be repeated as often as required


When is ESWL not effective?

Not used as first line treatment for stones > 2cms and less effective for lower pole stones

If not effective after two treatments then further treatments not justified

Often ineffective for treating cystine stones


What are the common places for a stone to get lodged?


What is IVU?

The IVU is a special diagnostic test that follows the time course of excretion of a radiopaque contrast dye through the kidneys, ureters (the tubes that carry urine from the kidneys to the bladder) and bladder after it is injected into a vein in your arm.


The discovery of X-rays and the use of contrast material in 1906 allowed accurate diagnosis and localisation of ureteric stones.


The introduction of the IVU revolutionised the diagnosis of ureteric stones.


Indications for open ureterolithotomy - open surgery for ureteric stones

Not suitable for laparoscopic approach.

  Failed ESWL or ureteroscopy.


Indications for ureteroscopy (endoscopic surgery)

Severe obstruction, uncontrollable pain, persistent haematuria, lack of progression, failed ESWL and patient occupation.


Lower ureteric stones have a higher success rate when compared with proximal stones


What are the minor and major complications of ureteroscpy?

Minor complications: 0-30%

Haematuria, fever, small ureteric perforation,  minor vesico-ureteric reflux.

Major complications:

Major ureteric perforation, ureteric avulsion, ureteral necrosis and stricture formation.


What are the presenting features of bladder stones?

Suprapubic / groin / penile pain

Dysuria, frequency, haematuria

Urinary infection (persistent)

Sudden interruption of urinary stream

Usually secondary to outflow obstruction


How are bladder stones usually treated?

Most treated endoscopically

Larger stones can be treated

  by open excision