Nerve and muscle degeneration and re-innervation Flashcards Preview

Foundations of Neuroscience > Nerve and muscle degeneration and re-innervation > Flashcards

Flashcards in Nerve and muscle degeneration and re-innervation Deck (12):
1

What would happen if a motor neurone in the PNS was damaged?

It has terminally differentiated
Permanent injury results in cell death
No mitosis = no replacemetn

2

Describe the nerve fibres found in type 1 muscle

Slow motor fibres (70m/s)
Small ~70microm
Excitability has low threshold
alpha2 neuron

3

Describe the nerve fibres found in type 2 muscle

Fast motor fibre (120m/s)
Large ~100microm
Excitability has a high threshold
alpha1 neuron

4

What happens in the soma of an axon?

Protein synthesis

5

What is the survival of cytoplasm dependent on?

Interaction with the nucleus

6

What protects peripheral nerves?

Schwann cells
Endoneurium
Perineurium
Epineurium

7

How many spinal nerves are there?

31

8

How many cranial nerves are there?

12

9

What does damage to the cell body result in?

Neuronal death

10

What is a dead neurone replaced with?

Fibrous tissue
(astrocytes/fibroblasts)

11

What does damage to the axon result in?

Possibility for recovery

12

What is the first stage in repairing a neuron?

Neuronal degeneration