NERVES: TRANSDUCTION AND SYNAPSES Flashcards Preview

M3 Pain and management > NERVES: TRANSDUCTION AND SYNAPSES > Flashcards

Flashcards in NERVES: TRANSDUCTION AND SYNAPSES Deck (9)
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1
Q

What is the Action potential?

A

All or none event

Voltage gated channels

Propagates along a nerve

2
Q

What is Graded Potential?

A

Local change in membrane potential

Triggering event:

– Receptor: Action of stimulus

• Mechanical, chemical or thermal gated channel

– Synaptic: Post synaptic membrane

3
Q

What is the Graded potentials - receptors?

A

Transduction at the nerve ending

Conversion of stimulus energy (e.g. mechanical) to electrical energy

By specific channels: – Mechanically sensitive ion channels

– Thermal

4
Q

Label the diagram

A
5
Q

What are synapses?

A

One way relay stations from pre- to post-synaptic

Plasticity (means the can change e.g. if damaged)

Mchemical realy station between 2 nerves

  • Normally chemical – neurotransmitters
6
Q

What are some types of neurotransmitters which can be released at a synapse?

Why ar neurotransmitters important?

A

neurotransmitters:

– Glutamate

– GABA

– Gamma-aminobutyric acid

– Acetylcholine

– Serotonin

– Noradrenaline

Neurotransmitters are targets for many commonly used medicines

7
Q

Where does the following happen on this diagram:

  • Graded synaptic potential
  • Action potential Initiation
  • Action potential propagation
A
8
Q

What is an example of an Inhibitory neurotransmitter ?

A

GABA

9
Q

What is the Presynaptic inhibition?

A

Results in decreased neurotransmitter release from presynaptic terminal

Axo-axonal synapse