Nervous 1 Pathologies Flashcards
(18 cards)
Name viral cause of Bell’s Palsy
Herpes Simplex 1
Guillain Barre Syndrom is an Auto Immune disease? Yes or No
Yes
Guillain Barre Sumptoms?
Ascending and progressive inflammation and demyelination of PNS
EBV Virus
Flue
(where antibodies formed against virus cross react with lipids in myelin (molecular mimicry)
Guillain Barre Syndrome Treatment
Emergency care, respirator intensive care. Plasma exchange (when patentiends blood plasma is removed and replaced)
Multiple Sclerosis (MS) - what is it ?
Its an Auto immunce inflammatory disease. Causing Demyelination of axons in CNS Neurons with Damage.
What age does MS usually occur? And do men or women tend to this this more?
20-25 years and in Woman more common
MS - what is the disease pattern?
Relapse - remit pattern (85% of cases)
What are the causes of MS?
Vitamin D Deficiency (biggest risk factor)
Vitamin B12 Deficiency
Genetic
Viruses like EBV, measles.
MS signs and Symptoms ?
Blindness, loss of vision
Double vision
Deafness and loss of balance
burning, pulling sensation
Tingling and loss of sensation
Bladder urgency and incontinence
Cognitive changes and depression
weakness
How do you diagnose MS?
MRI and CSF analysis
What diet is recommended for MS?
Ketogenic, anti-inflammatory diet
Vitamin D and B12 supplements
What is Motor Neuron Disease (MND)
It describes the progressive degeneration of motor neurons in the spinal cord, motor cortex and brain stem.
Current hypothesis focuses on abnormal mitochondrial function causing oxidative stress in motor neurons.
Does Motor Neuron Disease most affect men or women?
Men
MND Signs and symptoms?
Weakness of grip and upper limbs
dropping objects
wasting of hand muscles and tremor of limbs at rest
later stages can affect the legs (tripping) causing slurred speech.
People die 3-5 years after diagnosis. Usually of respiratory failure.
What is dementure?
dementia is a syndrome cause by a number of brain disorders which cause memory loss, decline in order aspects of cognition, difficulty performing daily activities.
What causes Dementure?
Due to cerebrovascular disease (e.g. due to stroke) and poor oxygen delivery.
The main cause of dementia is Alzheimer’s disease, which accounts for around 60–70% of all cases. It is a progressive neurodegenerative condition characterized by abnormal protein build-up (amyloid plaques and tau tangles) in the brain, leading to the death of brain cells and loss of brain function over time.
Alzheimers disease - what is it ?
Its a neurodegenerative disease of the cerebral cortex.
Alzheimer’s is linked to abnormal protein buildup in and around brain cells—amyloid plaques and tau tangles—which damage and kill neurons over time.
What is the pathyphysiology for alzheimerz?
Associated with abnormal protein deposition (beta amyloid) atrophy of neurons and less acetylcholine in the brain.
