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Flashcards in Neuro l Deck (57)
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1

CNS imaging of choice unless it's suspected meningitis, then do what?

MRI
lumbar puncture

2

Cholinergic agonist indic for Glaucoma that acts on muscarinic-R

pilocarpine

3

nicotine binds to ______ and induces what enzyme?

nicotinic-R
CYP1A2 - caffeine, theophylline, TCA's, warfarin

4

Overdose of Antipsychotics is called -_________
What is tx?

Neurolyptic Malignant Syndrome
Bromocriptine (dopamine agonist)

5

Antipsychotics MOA
ADR's

decrease dopamine
ADRs: tremors, tardive, blurred vision, hypotension, constipation, dry mouth, urinary retention, sexual dysfxn, drowsy, PROLACTIN

6

Antipsych indic for psychosis, N/V, hiccoughs

prochlorperazine
decrease dopamine
ADR: PROLACTIN, tremors, tardive, etc.

7

injectable Antipsychotic indic for Psychosis, Tourettes, Huntingtons

Haloperidol
+ H1 blockade so extra powerful!

8

Indic for psychosis, schizo, bipolar
Caution in children

Respiradone
oral
p450

9

No dopamine blocking are what category of antipsychotics

Atypical

10

Why use SAM-E

used to make excitatory neurotransmitters

11

Cocaine, Buproprion, Amphetamine, Benzatropine all do what?

block reuptake of dopamine so more dopamine around

12

tricyclic and amphetamines all do what?

block reuptake of NE

13

indic for depression, narcolepsy, phobias, and parkinson's

MAO-I

14

MAO-I MOA and drug?

block metabolism of dopa, NE, SE
suppresses REM sleep
phenelzine (nardil)

15

What drug can increase seizure threshold and increases NE and DOPA

bupropion

16

SSRI's

fluoxetin (prozac)
sertraline
paroxetine - paxil
citalopram - celexa
Lexapro

17

What AA can you use when tapering off or on SSRIs?

tryptophan

18

Non-SSRI used for sleep commonly but ironic withdrawal sx

trazadone
- rebound insomnia

19

SE syndrome

look sick
F, hyperreflexia, BP changes, coma, death

20

enhance serotonin with what supps

B6/niacinamide, trypt, 5HTP

21

if SSRI's don't work can try what drug?

Venlafaxine
modified 5HT effectors, SE & NE

22

indic for neuropathic pain, fibro

pregabalin (lyrica)

23

anxiolytic wo sedating or euphoric effects
does not act on GABA
SE, dopa, NE

buspirone

24

GABA drugs (3):
have what kind of effect?

alcohol, barbs, benzos
amnesia effect

25

Indic for anxiety, wound healing, muscle spasms
class of drugs

glycine-R working w chloride
Caution in bipolar Pts because excitatory

26

long-term tx of seizure drugs

phenytoin, carbamazapine
decrease movement of Na, Ca, K

27

If first presenting with epilepsy, then must do what first?

MRI to ro tumor

28

2 Bipolar Drugs

lithium - sodium ions in brain
gabapentin - GABA agonist

29

LITHIUM ADR
Caution with ____

HYPOTHYROID, coma, KD probs
LOW SODIUM DIET

30

if a kid is on ritalin (methylphenidate), put them on which supp?

zinc helps the drug to work