NEUROLEPTICS, TRANQUILIZERS. SEDATIVES

Question 1

1. A 40 year-old patient was admitted to the psychiatric clinic in an ^agitated state^. He was ^aggressive^, and delirated. Indicate the best drug to be given

A. Aminazine (chlorpromazine)
B. Sodium bromide
C. Diazepam
D. Tinctura Valerianae
E. Peserpinum

Answer 1

Aminazine (chlorpromazine)

Question 2

2. A man with disorders of psychoemotional state and sleeplessness, was treated with ^diazepamum^. Upon which receptors this drug influence?

A. Benzodiazepine receptors
B. Alfa-adrenoreceptors
C. Beta-adrenoreceptors 
D. M-cholinoceptors
E. N-cholinoceptors

Answer 2

Benzodiazepine receptors

Question 3

3. Impairment of movement co-ordination, shivering of the hands and sleepiness developed in the patient had been suffering from schizophrenia under the treatment by ^psychotropic drugs^. Indicate this group of drugs.

A. Neuroleptics
B. Analgesics
C. Tranquilizers
D. Antidepressants 
E. Psyco stimulants

Answer 3

Neuroleptics

Question 4

4. Introduction of aminazine(chlor-promazine), which was made to a patient who had been suffering from chronic alcholism for elimination of agression and delirium, caused loss of consiousness in this patient. Indicate the probable reason of this complication.

A. Orthostatic collapse.
B. Inhibition of the reticular formation.
C. Impairment of coronary circulation.
D. Suppression of the limbic system. .
E. Impairment of oxidative processes in the brain tissue.

Answer 4

Orthostatic collapse

Question 5

5. Indicate the drug for elimination of the acute psychosis from the group of ^derivatives of phenothiazine^.

A. Aminazinum (chlorpromazine)
B. Diazepam.
C. Haloperidol 
D. Amitriptylin
E. Natrii oxybutyras (oxybate sodium)

Answer 5

Aminazinum (chlorpromazine)

Question 6

6. Determine the group of drugs which doesn’t cause drug dependence.

A. Neuroleptics
B. Tranquilizers 
C. Barbiturates
P. Opioid analgesics 
E. Psychostimulants -phenylalkylamine derivatives

Answer 6

Neuroleptics

Question 7

7. A doctor administered aminazinum (chlorpromazine) to the patient suffering from schizophrenia to eliminate delirium, hallucinations, to decrease aggression and psychomotor excitement. What is the mechanism of antipsychotic action of aminazinum?

A. Excitation of M-cholinoreceptors in the CNS
B. Stimulation of opioid receptors
C. Blockade of adrenoreceptors and dopamine
receptors in the CNS
D. Excitement of adrenoreceptors and dopamine
receptors in the CNS.
E. Inhibition of MAO

Answer 7

Blockade of adrenoreceptors and dopamine

receptors in the CNS

Question 8

8. A neuroleptic (butyrophenone derivative) was
   administered to a patient with alcohol psychosis.
   Determine this drug.

A. Aminazinum (chlorpromazine)
B. Sulpirid
C. Diazepam
D. Triftazinum (trifluoperazine) 
E. Haloperidol

Answer 8

Haloperidol

Question 9

9. ^Neuroleptoanalgesia^ was made to a patient because of myocardial infarction. What drug from the group of neuroleptics is used more often in combination with fentanyl?

A. Droperidol
B. Aethaperazinum (perphenazine)
C. Diazepam
D. Chlozepidum (chlordiazepoxide) 
E. Sulpind

Answer 9

Droperidol