Flashcards in Neuropathology Deck (2)
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1
Q
- UMN injury? (3)
- LMN injury? (3)
- PNS injury effects?
1. ) ALS: Nerves? Speech? Bowel/bladder? >M? Affects? Riluzole?
2. ) CMT: Effect? PMP22 Gene: CMT1A? HNPP?
3. ) MG: Often have? Steroids? - Mononeuropathy? Radiculopathy? Plexopathy?
A
- Spastic tone, hyperrelfexes, emotional
- Lower tone, Lower reflexes, atrophy
- Afferent and efferent
- UMN and LMN; slurred; Fine; yes; Corticospinal tracts; Glu inhibitor
- Demylenation; duplication on 17 = distal weakness; deletion on 17 = focal weakness
- Thymoma; yes
- 1 nerve root; problem near root; effects network
2
Q
- Wallerian Degen.?
- Neuronal cytoskeloton? May be related to?
- Glial Fib. Acidic Protein? Used for?
- Myopathy: Weak? CK?
- Denervation: Weak CK?
- Distal axonopathy?
- Segmental demylen: Onion bulb?
- Order of clinical regeneration?
A
- Transected neuron
- Perikaryon; Alzheimers
- Astrocyte cytoplasm protein; scars
- Prox., high
- Distal; normal
- Degen from most distal nerves then moves prox
- yes
- Autonomic, sensory, motor