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Flashcards in Neuropathology Deck (2)
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1
Q
  • UMN injury? (3)
  • LMN injury? (3)
  • PNS injury effects?
    1. ) ALS: Nerves? Speech? Bowel/bladder? >M? Affects? Riluzole?
    2. ) CMT: Effect? PMP22 Gene: CMT1A? HNPP?
    3. ) MG: Often have? Steroids?
  • Mononeuropathy? Radiculopathy? Plexopathy?
A
  • Spastic tone, hyperrelfexes, emotional
  • Lower tone, Lower reflexes, atrophy
  • Afferent and efferent
  • UMN and LMN; slurred; Fine; yes; Corticospinal tracts; Glu inhibitor
  • Demylenation; duplication on 17 = distal weakness; deletion on 17 = focal weakness
  • Thymoma; yes
  • 1 nerve root; problem near root; effects network
2
Q
  • Wallerian Degen.?
  • Neuronal cytoskeloton? May be related to?
  • Glial Fib. Acidic Protein? Used for?
  • Myopathy: Weak? CK?
  • Denervation: Weak CK?
  • Distal axonopathy?
  • Segmental demylen: Onion bulb?
  • Order of clinical regeneration?
A
  • Transected neuron
  • Perikaryon; Alzheimers
  • Astrocyte cytoplasm protein; scars
  • Prox., high
  • Distal; normal
  • Degen from most distal nerves then moves prox
  • yes
  • Autonomic, sensory, motor