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Flashcards in Neurotoxicants Deck (11):
0

Agents that cause chronic encephalopathy including?

Lead
Arsenic
Manganese
Mercury
Solvents (painter's syndrome)
Organophosphate

(LAMs & SO)

1

Painter's syndrome?

Long term exposure to solvent, c/o vague cognitive difficulty, particularly on memory, also on mode and affect.

2

4 mentals that cause peripheral neuropathies are?

Lead
Arsenic
Mercury
Thallium

(LAM T)

3

Central neurotoxicants

Carbon disulfide
Chlorinated hydrocarbons
CO
Metals - arsenic, lead (epilepsy), manganese (Parkinson's), mercury
Solvents - benzene, halothane, methylene chloride, perchloroethylene (PERC), styrene, toluene, trichloroethylene (TCE)

4

N-hexane & methyl n-butylketone, can cause what neuro disorder?

Peripheral neuropathy

(N-hexane used in rubber industry)
(Methyl n-butylketone used for paint)

5

Toluene can cause what neuro disorder?

Encephalopathy

(Toluene use in glue sniffer)

6

Cobalt & manganese impact what part of the brain?

Basal ganglia
Parkinson's-like Sx

7

Causes of Parkinsonism

Carbon disulfide
Carbon monoxide
Manganese
N-methyl-4-phenyltetrahydropyridine (MPTP) ( use in rat to create Parkinson's animal model)

(Big 4)

8

Central neurotoxicants ?

Carbon disulfide
Chlorinated hydrocarbons
Carbon monoxide
Metals -
Lead (epilepsy)
arsenic
mercury
manganese (Parkinson's )
Solvents -
benzene
halothane
Methylene chloride
Perchloroethylene (PERC)
Styrene
Toluene
Trichloroethylene (TCE)

9

Agent that causes peripheral neuropathies?

Metals:
Lead
Arsenic
Mercury
Thallium
Organophosphate & carbamate pesticides
Acrylamide monomer
Carbon disulfide

10

Affecting trigeminal N

Trichloroethylene